Arthritis Research & Therapy

official impact factor 4.36

Open Access Highly Access Research article

Trends towards an improved disease state in rheumatoid arthritis over time: influence of new therapies and changes in management approach: analysis of the EMECAR cohort

Isidoro González-Alvaro1*, Miguel A Descalzo2, Loreto Carmona2 and the EMECAR Study Group

Author Affiliations

1 Rheumatology Service, Hospital Universitario de la Princesa, c/Diego de León 62, Madrid 28006, Spain

2 Research Unit, Fundación Española de Reumatología, c/Marques del Duero 5, 1°, Madrid 28001, Spain

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Arthritis Research & Therapy 2008, 10:R138 doi:10.1186/ar2561

Published: 26 November 2008

Additional files

Additional file 1:

A Word file listing the collaborators in the EMECAR study.

Format: DOC Size: 24KB Download file

This file can be viewed with: Microsoft Word Viewer

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Additional file 2:

An Adobe file containing a figure that shows the flowchart of the EMECAR study, providing relevant information about the dropouts along the follow-up.

Format: PDF Size: 78KB Download file

This file can be viewed with: Adobe Acrobat Reader

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Additional file 3:

A Word file containing a table that presents the characteristics of the studied patients and the nonstudied patients in the multivariable analysis of each variable: disease activity, functional disability and radiological damage.

Format: RTF Size: 51KB Download file

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Additional file 4:

An image file containing a graph of reasons for discontinuation during follow-up among therapies. The smaller the space between levels of different variables, the greater the association between them. AM, antimalarials; aTNF, TNF antagonists; GS, parenteral gold salts; LEF, leflunomide; MTX, methotrexate; SSZ, sulfasalazine.

Format: JPEG Size: 8KB Download file

Open Data