Figure 6.

Redefining the boundaries for the Aec2 Sjögren Syndrome (SjS) susceptibility genetic locus. Based on the disease profiling of the C57BL/6.NOD-Aec1Aec2R(n) recombinant inbred (RI) lines, the boundaries of the Aec2 genetic region containing SjS susceptibility genes have been temporarily reset to position 79 ± 5 cM of chromosome 1 (shaded gray gradient rectangular box). Possible quantitative trait loci genes may reside a few centimorgans centromeric to this region (unshaded rectangular box).