Table 5 |
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|
Centers for Disease Control and Prevention reference standards tested for anti-Rib-P antibodies |
|||||||
|
Sample |
Specificity |
ELISA, RUa |
Interpretation |
ALBIA, LUb |
Interpretation |
LIA |
Interpretation |
|
|
|||||||
|
CDC1 |
Anti-dsDNA |
1.0 |
Borderline |
143 |
Negative |
0 |
Negative |
|
CDC2 |
Anti-SS-B/La |
0.3 |
Negative |
97 |
Negative |
0 |
Negative |
|
CDC3 |
Speckled ANA |
0.4 |
Negative |
80 |
Negative |
0 |
Negative |
|
CDC4 |
U1-RNP |
0.6 |
Negative |
157 |
Negative |
0 |
Negative |
|
CDC5 |
Sm |
0.6 |
Negative |
89 |
Negative |
0 |
Negative |
|
CDC6 |
Nucleolar; anti-fibrillarin |
0.3 |
Negative |
210 |
Negative |
0 |
Negative |
|
CDC7 |
SS-A/Ro60 |
0.8 |
Negative |
149 |
Negative |
0 |
Negative |
|
CDC8 |
Centromere |
0.5 |
Negative |
119 |
Negative |
0 |
Negative |
|
CDC9 |
Topoisomerase-I |
0.9 |
Negative |
166 |
Negative |
0 |
Negative |
|
CDC10 |
Jo-1 |
0.3 |
Negative |
75 |
Negative |
0 |
Negative |
|
CDC11 |
PM/Scl |
0.5 |
Negative |
126 |
Negative |
0 |
Negative |
|
CDC12 |
Rib-P |
6.6 |
Positive |
11,664 |
Positive |
3 |
Positive |
|
|
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|
aCutoff = 1.5 relative units (RU); bcutoff = 350 luminescence units (LU). ALBIA, addressable laser bead immunoassay; CDC, Centers for Disease Control and Prevention; dsDNA, double-stranded DNA; ELISA, enzyme-linked immunosorbent assay; LIA, line immunoassay; Rib-P, ribosomal P protein. |
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|
Mahler et al. Arthritis Research & Therapy 2008 10:R131 doi:10.1186/ar2548 |
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