Expression changes in transcripts associated with disease progression. Scatter plot showing the expression levels of dysregulated probe sets expressed in (NZBxNZW)F1 kidneys of mice with lupus nephritis (older mice) (Y axis) compared with expression levels in asymptomatic (younger) mice (X axis). (a) Expression levels of 547 non-immunoglobulin (Ig) probe sets significantly associated with disease, 46% of which are expressed at higher levels in diseased kidney. (b) Expression levels of 195 immunoglobulin probes sets, 100% of which are expressed at higher levels in diseased kidney.
Reddy et al. Arthritis Research & Therapy 2008 10:R127 doi:10.1186/ar2541