Figure 11.

Shortest path from the mTOR pathway to lupus nephritis genes and lupus genes. The information shown schematically in this figure can be viewed in table form in Additional file 4. Solid lines indicate direct interactions and dotted lines indicate indirect interactions. mTOR pathway is indicated in the red box, the lupus nephritis genes in the yellow box and the lupus genes in the green box. The green colour nodes indicate genes expressed at higher levels in disease and red indicates lower levels in disease. Grey colour indicates that the fold change and FDR p < 0.05 filters were not met. The names of the genes are in "nodes". The shape of the nodes is related to gene function/family membership. The lines between the nodes represent the connectivity between genes. Solid lines indicate direct protein-protein interactions. Dotted lines represent indirect interactions.