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Volume 10 Issue 6
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Comment |
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Epitope spreading in animal models: array of hope in rheumatoid arthritis and multiple sclerosis
Karin Lundberg, Patrick J Venables Arthritis Research & Therapy 2008, 10:122 (25 November 2008)
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Vitamin D or hormone D deficiency in autoimmune rheumatic diseases, including undifferentiated connective tissue disease
Maurizio Cutolo Arthritis Research & Therapy 2008, 10:123 (2 December 2008)
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Plasma gelsolin as a biomarker of inflammation
Mark J DiNubile Arthritis Research & Therapy 2008, 10:124 (3 December 2008)
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More intrinsic parameters should be used in assessing degeneration of articular cartilage with quantitative ultrasound
Yong-Ping Zheng, Yan-Ping Huang Arthritis Research & Therapy 2008, 10:125 (16 December 2008)
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Interferon-induced versus chemokine transcripts as lupus biomarkers
Mary K Crow, Kyriakos A Kirou Arthritis Research & Therapy 2008, 10:126 (18 December 2008)
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Review |
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Regulatory T cells in systemic lupus erythematosus: past, present and future
David A Horwitz Arthritis Research & Therapy 2008, 10:227 (14 November 2008)
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NOD-like receptors and inflammation
Rebeccah J Mathews, Michael B Sprakes, Michael F McDermott Arthritis Research & Therapy 2008, 10:228 (25 November 2008)
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Glomerular matrix metalloproteinases and their regulators in the pathogenesis of lupus nephritis
Anders Tveita, Ole Rekvig, Svetlana N Zykova Arthritis Research & Therapy 2008, 10:229 (1 December 2008)
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Antiphospholipid syndrome
Gerard Espinosa, Ricard Cervera Arthritis Research & Therapy 2008, 10:230 (15 December 2008)
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Report |
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Levels of gastrin-releasing peptide and substance P in synovial fluid and serum correlate with levels of cytokines in rheumatoid arthritis
Ola Grimsholm, Solbritt Rantapää-Dahlqvist, Sture Forsgren Arthritis Research & Therapy 2008, 10:410 (12 November 2008)
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Research |
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Mapping similarities in mTOR pathway perturbations in mouse lupus nephritis models and human lupus nephritis
Padmalatha S Reddy, Holly M Legault, Joseph P Sypek, Mark J Collins, Elizabeth Goad, Samuel J Goldman, Wei Liu, Stuart Murray, Andrew J Dorner, Margot O'Toole Arthritis Research & Therapy 2008, 10:R127 (3 November 2008)
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Impact of low-dose prednisolone on bone synthesis and resorption in early rheumatoid arthritis: experiences from a two-year randomized study
Inga-Lill Engvall, Björn Svensson, Birgitta Tengstrand, Kerstin Brismar, Ingiäld Hafström, the BARFOT study group Arthritis Research & Therapy 2008, 10:R128 (5 November 2008)
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Analysis of the precision and sensitivity to change of different approaches to assess cartilage loss by quantitative MRI in a longitudinal multicentre clinical trial in patients with knee osteoarthritis
Jean-Pierre Raynauld, Johanne Martel-Pelletier, François Abram, Marc Dorais, Boulos Haraoui, Denis Choquette, Peter Bias, Karl H Emmert, Stefan Laufer, Jean-Pierre Pelletier Arthritis Research & Therapy 2008, 10:R129 (5 November 2008)
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Arthritogenic T cell epitope in glucose-6-phosphate isomerase-induced arthritis
Keiichi Iwanami, Isao Matsumoto, Yoko Tanaka, Asuka Inoue, Daisuke Goto, Satoshi Ito, Akito Tsutsumi, Takayuki Sumida Arthritis Research & Therapy 2008, 10:R130 (7 November 2008)
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Limited reliability of the indirect immunofluorescence technique for the detection of anti-Rib-P antibodies
Michael Mahler, Jennifer T Ngo, Johannes Schulte-Pelkum, Tanja Luettich, Marvin J Fritzler Arthritis Research & Therapy 2008, 10:R131 (11 November 2008)
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Characteristics of repair tissue in second-look and third-look biopsies from patients treated with engineered cartilage: relationship to symptomatology and time after implantation
Paola Brun, Sally C Dickinson, Barbara Zavan, Roberta Cortivo, Anthony P Hollander, Giovanni Abatangelo Arthritis Research & Therapy 2008, 10:R132 (11 November 2008)
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Therapeutic efficacy of intra-articular adrenomedullin injection in antigen-induced arthritis in rabbits
Toshiyuki Okura, Kousuke Marutsuka, Hiroaki Hamada, Tomohisa Sekimoto, Tsuyoshi Fukushima, Yujiro Asada, Kazuo Kitamura, Etsuo Chosa Arthritis Research & Therapy 2008, 10:R133 (13 November 2008)
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Cartilage oligomeric matrix protein deficiency promotes early onset and the chronic development of collagen-induced arthritis
Hui Geng, Stefan Carlsen, Kutty Nandakumar, Rikard Holmdahl, Anders Aspberg, Åke Oldberg, Ragnar Mattsson Arthritis Research & Therapy 2008, 10:R134 (14 November 2008)
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Collagen-specific T-cell repertoire in blood and synovial fluid varies with disease activity in early rheumatoid arthritis
Francesco Ria, Romina Penitente, Maria De Santis, Chiara Nicolò, Gabriele Di Sante, Massimiliano Orsini, Dario Arzani, Andrea Fattorossi, Alessandra Battaglia, Gian Ferraccioli Arthritis Research & Therapy 2008, 10:R135 (17 November 2008)
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T-614, a novel immunomodulator, attenuates joint inflammation and articular damage in collagen-induced arthritis
Fang Du, Liang-jing Lü, Qiong Fu, Min Dai, Jia-lin Teng, Wei Fan, Shun-le Chen, Ping Ye, Nan Shen, Xin-fang Huang, Jie Qian, Chun-de Bao Arthritis Research & Therapy 2008, 10:R136 (19 November 2008)
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Editor’s summary
T-614, a novel oral anti-rheumatic agent, effectively attenuates joint inflammation and offers significant protection against bone and cartilage destruction in an experimental model of collagen-induced arthritis.
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Identification of possible candidate genes regulating Sjögren's syndrome-associated autoimmunity: a potential role for TNFSF4 in autoimmune exocrinopathy
Cuong Q Nguyen, Janet G Cornelius, Lauren Cooper, Jonathan Neff, Joann Tao, Byung Lee, Ammon B Peck Arthritis Research & Therapy 2008, 10:R137 (25 November 2008)
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Trends towards an improved disease state in rheumatoid arthritis over time: influence of new therapies and changes in management approach: analysis of the EMECAR cohort
Isidoro González-Alvaro, Miguel Descalzo, Loreto Carmona, the EMECAR Study Group Arthritis Research & Therapy 2008, 10:R138 (26 November 2008)
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Editor’s summary
Rheumatoid arthritis disease activity has improved independently of the availability of new drugs since the year 2000 according to a cohort study, most likely due to better management of existing treatments.
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Retinoid X receptor and peroxisome proliferator-activated receptor-gamma agonists cooperate to inhibit matrix metalloproteinase gene expression
Peter S Burrage, Adam C Schmucker, Yanqing Ren, Michael B Sporn, Constance E Brinckerhoff Arthritis Research & Therapy 2008, 10:R139 (1 December 2008)
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Synergistic role of c-Myc and ERK1/2 in the mitogenic response to TGFβ-1 in cultured rat nucleus pulposus cells
Tomoko Nakai, Joji Mochida, Daisuke Sakai Arthritis Research & Therapy 2008, 10:R140 (5 December 2008)
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All-trans retinoic acid suppresses interleukin-6 expression in interleukin-1-stimulated synovial fibroblasts by inhibition of ERK1/2 pathway independently of RAR activation
Mélanie Kirchmeyer, Meriem Koufany, Sylvie Sebillaud, Patrick Netter, Jean-Yves Jouzeau, Arnaud Bianchi Arthritis Research & Therapy 2008, 10:R141 (10 December 2008)
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Antibodies to mutated citrullinated vimentin for diagnosing rheumatoid arthritis in anti-CCP-negative patients and for monitoring infliximab therapy
Pascale Nicaise Roland, Sabine Grootenboer Mignot, Alessandra Bruns, Margarita Hurtado, Elisabeth Palazzo, Gilles Hayem, Philippe Dieudé, Olivier Meyer, Sylvie Chollet Martin Arthritis Research & Therapy 2008, 10:R142 (10 December 2008)
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Editor’s summary
Antibodies to mutated citrullinated vimentin complement the use of anti-cyclic citrullinated peptides antibodies in the diagnosis of rheumatoid arthritis, and may be useful for monitoring infliximab therapy.
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Vastus medialis cross-sectional area is positively associated with patella cartilage and bone volumes in a pain-free community-based population
Patricia A Berry, Andrew J Teichtahl, Ana Galevska-Dimitrovska, Fahad S Hanna, Anita E Wluka, Yuanyuan Wang, Donna M Urquhart, Dallas R English, Graham G Giles, Flavia M Cicuttini Arthritis Research & Therapy 2008, 10:R143 (15 December 2008)
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Incremental cost effectiveness of proton pump inhibitors for the prevention of non-steroidal anti-inflammatory drug ulcers: a pharmacoeconomic analysis linked to a case-control study
Harald E Vonkeman, Louise MA Braakman-Jansen, Rogier M Klok, Maarten J Postma, Jacobus RBJ Brouwers, Mart AFJ van de Laar Arthritis Research & Therapy 2008, 10:R144 (16 December 2008)
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Lack of association between glucocorticoid use and presence of the metabolic syndrome in patients with rheumatoid arthritis: a cross-sectional study
Tracey E Toms, Vasileios F Panoulas, Karen MJ Douglas, Helen R Griffiths, George D Kitas Arthritis Research & Therapy 2008, 10:R145 (17 December 2008)
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Editor’s summary
Long term exposure to glucocorticoids does not appear to be associated with a higher prevalence of the metabolic syndrome in patients with rheumatoid arthritis, finds a cross-sectional study.
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Increased expression of lipocalin-type prostaglandin D2 synthase in osteoarthritic cartilage
Nadia Zayed, Xinfang Li, Nadir Chabane, Mohamed Benderdour, Johanne Martel-Pelletier, Jean-Pierre Pelletier, Nicolas Duval, Hassan Fahmi Arthritis Research & Therapy 2008, 10:R146 (18 December 2008)
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Monocytes are essential for inhibition of synovial T-cell glucocorticoid-mediated apoptosis in rheumatoid arthritis
Dimitrios Makrygiannakis, Shankar Revu, Petra Neregård, Erik af Klint, Omri Snir, Cecilia Grundtman, Anca Catrina Arthritis Research & Therapy 2008, 10:R147 (19 December 2008)
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Correspondence |
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Fibromyalgia and sleep-disordered breathing: the missing link
Denis Martinez, Cristiane Cassol Arthritis Research & Therapy 2008, 10:408 (25 November 2008)
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Fibromyalgia and sleep-disordered breathing: the missing link – author's response
Jean Eisinger Arthritis Research & Therapy 2008, 10:409 (25 November 2008)
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