Table 4

Association of C/T polymorphism of the GDF5 gene with CDH when stratified by severity

Groups compared

TT vs. other combined

CC vs. other combined

T allele vs. C allele

All genotype





OR

P value

95% CI

OR

P value

95% CI

OR

P value

95% CI

P value


Patients with hip dislocation (n = 264) vs all controls (n = 622)

1.41

0.023

1.05 to 1.89

0.49

0.044

0.24 to 0.99

1.40

0.0078

1.09 to 1.79

0.028

Patients with hip subluxation (n = 53) vs all controls (n = 622)

1.35

0.31

0.76 to 2.41

0.49

0.32

0.12 to 2.08

1.36

0.22

0.83 to 2.20

0.46

Patients with hip instability (n = 21) vs all controls (n = 622)

1.64

0.29

0.65 to 4.11

0.63

0.65

0.08 to 4.77

1.51

0.30

0.69 to 3.29

0.57


CDH = congenital dysplasia of the hip; CI = confidence interval; GDF5 = growth differentiate factor 5; OR = odds ratio.

Dai et al. Arthritis Research & Therapy 2008 10:R126   doi:10.1186/ar2540

Open Data