Table 3

Association of C/T polymorphism of the GDF5 gene with CDH when stratified by gender

Groups compared

TT vs. other combined

CC vs. other combined

T allele vs. C allele

All genotype





OR

P value

95% CI

OR

P value

95% CI

OR

P value

95% CI

P value


All patients (n = 338) vs all controls (n = 622)

1.41

0.013

1.08 to 1.85

0.50

0.029

0.27 to 0.94

1.40

0.0037

1.11 to 1.75

0.014

Female patients (n = 291) vs female controls (n = 316)

1.52

0.012

1.10 to 2.10

0.50

0.061

0.24 to 1.05

1.46

0.0053

1.21 to 1.91

0.020

Male patients (n = 47) vs male controls (n = 306)

1.24

0.51

0.66 to 2.33

0.55

0.42

0.12 to 2.40

1.27

0.38

0.75 to 2.14

0.65


CDH = congenital dysplasia of the hip; CI = confidence interval; GDF5 = growth differentiate factor 5; OR = odds ratio.

Dai et al. Arthritis Research & Therapy 2008 10:R126   doi:10.1186/ar2540

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