Table 2

Relationship between low serum levels of vitamin D and clinical/serological manifestations of undifferentiated connective tissue disease patients

Correlation between clinical symptoms and vitamin D insufficiency

P value

OD

(95% CI)

Xerostomia/xerophtalmia

0.8276

0.8909

(0.3768–2.107)

Polyarthritis

0.4834

0.7621

(0.3772–1.540)

Skin lesion

0.0046

2.987

(1.397–6.385)

Pleuritis

0.0346

5.367

(1.078–26.719)

Central and peripheral nervous system manifestations

1

0.8344

(0.1924–3.619)

Raynaud phenomenon

0.5331

0.7407

(0.3178–1.726)

Oesophageal involvement

0.3448

1.650

(0.6569–4.144)

Correlation between antibodies and vitamin D insufficiency

Anti-U1-ribonucleoprotein antibody

0.0240

5.083

(1.286–20.094)

Anti-SSA antibody

0.029

3.474

(1.147–10.520)

Anti-cyclic citrullinated peptide antibody

0.0001

12.0

(3.541–42.036)

Anti-double-stranded DNA antibody

0.2551

0.4896

(0.1751–1.369)

Anti-neutrophil cytoplasmic antibody

0.2978

0.4024

(0.064–2.51)

Anti-cardiolipin antibody

0.3728

1.715

(0.6535–4.501)

Anti-SSB antibody

0.2945

0.5254

(0.1484–1.860)

OD, Odds ratio; CI, confidence interval

Zold et al. Arthritis Research & Therapy 2008 10:R123   doi:10.1186/ar2533