Table 2

Citrullinated peptides detected in experimental autoimmune encephalomyelitis brain tissue

Protein name

Accession number

Total score

Number of peptides

%coverage

cit peptide

p value


ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit

[Genbank: 20070412]

205

5

54

KFSPLTANLMNLLAENG(cit)L

0.041

RLASLSEKPPAIDWAYY(cit)A

0.016


Peroxisomal membrane protein 20

[Genbank: 6746357]

296

4

50

KATDLLLDDSLVSLFGNR(cit)L

0.24


Phosphatidylethanolamine binding protein 1

[Genbank: 84794552]

376

5

52

KLYTLVLTDPDAPS(cit)K

0.088

KVLTPTQVMN(cit)PSSISWDGLDPGK.L

0.44

KGNDISSGTVLSDYVGSGPPSGTGLH(cit)Y

7.1e-10


Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, ΞΆ

[Genbank: 6756041]

506

14

63

KIETEL(cit)DICNDVLSLLEKF

0.0013

KTAFDEAIAELDTLSEES YKDSTLIMQLL(cit)D

2.1e-07


Malate dehydrogenase 2, NAD

[Genbank: 31982186]

650

11

61

KVDFPQDQLATLTG(cit)I

0.0025


Glyceraldehyde-3-phosphate dehydrogenase

[Genbank: 55153885]

523

8

41

KLVINGKPTIFQE(cit)D

0.096


Phosphoglycerate kinase 1

[Genbank: 146345481]

143

4

18

KDCVGPEVENACANPAAGTVILLENL(cit)F

0.066


Tubulin, beta 2c

[Genbank: 13542680]

822

13

46

RSGPFGQIF(cit)PDNFVFGQSGAGNNWAKG

0.0056


Atp5b protein

[Genbank: 23272966]

483

15

42

RT(cit)EGNDLYHEMIESGVINLKD

0.00035

KSLQDIIAILGMDELSEEDKLTVS(cit)A

9.8e-06


Kidd et al. Arthritis Research & Therapy 2008 10:R119   doi:10.1186/ar2523

Open Data