Table 1 |
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|
Minor allele frequencies and P values for 52 tag single nucleotide polymorphisms in the STAT1-STAT4 region in the first screening |
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|
Minor allele frequency |
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|
SNP |
Chromosomal positiona |
Minor allele |
SLE patients (n = 105) |
Controls (n = 102) |
P value |
|
|
|||||
|
rs3771300 |
191543841 |
C |
0.305 |
0.309 |
0.929 |
|
rs7575823 |
191544163 |
A |
0.167 |
0.147 |
0.584 |
|
rs16824035 |
191545879 |
A |
0.057 |
0.074 |
0.500 |
|
rs1914408 |
191548221 |
A |
0.271 |
0.314 |
0.344 |
|
rs2066804 |
191550004 |
A |
0.471 |
0.480 |
0.855 |
|
rs2280235 |
191552075 |
A |
0.486 |
0.471 |
0.758 |
|
rs3755312 |
191554236 |
C |
0.181 |
0.176 |
0.905 |
|
rs2280234 |
191558344 |
G |
0.162 |
0.186 |
0.513 |
|
rs2280232 |
191559011 |
C |
0.143 |
0.123 |
0.543 |
|
rs11887698 |
191563119 |
G |
0.327 |
0.304 |
0.629 |
|
rs7562024 |
191563766 |
G |
0.090 |
0.108 |
0.554 |
|
rs11904548 |
191567235 |
A |
0.162 |
0.137 |
0.482 |
|
rs12693591 |
191568747 |
A |
0.257 |
0.235 |
0.606 |
|
rs16833155 |
191569622 |
A |
0.043 |
0.054 |
0.600 |
|
rs2066805 |
191571146 |
G |
0.038 |
0.054 |
0.442 |
|
rs11677408 |
191574860 |
A |
0.129 |
0.108 |
0.514 |
|
rs2030171 |
191577408 |
G |
0.329 |
0.309 |
0.666 |
|
rs11693463 |
191578156 |
G |
0.195 |
0.196 |
0.983 |
|
rs11885069 |
191578869 |
A |
0.162 |
0.137 |
0.482 |
|
rs10199181 |
191581798 |
T |
0.267 |
0.265 |
0.964 |
|
rs2066802 |
191582912 |
G |
0.257 |
0.255 |
0.956 |
|
rs13029532 |
191584146 |
C |
0.082 |
0.103 |
0.457 |
|
rs3024904 |
191603447 |
A |
0.112 |
0.141 |
0.400 |
|
rs3024936 |
191603621 |
C |
0.024 |
0.055 |
0.112 |
|
rs1517351 |
191604290 |
C |
0.490 |
0.464 |
0.602 |
|
rs3024896 |
191604961 |
A |
0.448 |
0.412 |
0.461 |
|
rs925847 |
191605785 |
A |
0.538 |
0.490 |
0.330 |
|
rs3024886 |
191608694 |
A |
0.457 |
0.417 |
0.407 |
|
rs6715106 |
191621279 |
G |
0.067 |
0.083 |
0.520 |
|
rs16833215 |
191622044 |
G |
0.495 |
0.441 |
0.270 |
|
rs1400654 |
191623918 |
T |
0.066 |
0.083 |
0.524 |
|
rs3024861 |
191632851 |
T |
0.471 |
0.397 |
0.127 |
|
rs1517352 |
191639709 |
A |
0.481 |
0.397 |
0.086 |
|
rs10168266 |
191644049 |
A |
0.400 |
0.245 |
7.6 × 10-4 |
|
rs7594501 |
191646845 |
A |
0.114 |
0.152 |
0.250 |
|
rs16833239 |
191648505 |
A |
0.110 |
0.152 |
0.200 |
|
rs7601754 |
191648696 |
G |
0.129 |
0.178 |
0.162 |
|
rs11889341 |
191651987 |
A |
0.443 |
0.299 |
0.003 |
|
rs16833249 |
191656517 |
G |
0.567 |
0.480 |
0.079 |
|
rs6434435 |
191662109 |
A |
0.099 |
0.141 |
0.192 |
|
rs7574865 |
191672878 |
A |
0.471 |
0.324 |
0.002 |
|
rs12463658 |
191673589 |
C |
0.581 |
0.471 |
0.025 |
|
rs6752770 |
191681808 |
G |
0.205 |
0.245 |
0.326 |
|
rs1551443 |
191704763 |
A |
0.238 |
0.206 |
0.431 |
|
rs2356350 |
191710783 |
G |
0.510 |
0.407 |
0.036 |
|
rs10189819 |
191716994 |
G |
0.133 |
0.118 |
0.630 |
|
rs7596818 |
191717555 |
A |
0.320 |
0.295 |
0.580 |
|
rs11685878 |
191717700 |
A |
0.429 |
0.431 |
0.954 |
|
rs12991409 |
191717762 |
G |
0.100 |
0.113 |
0.674 |
|
rs12327969 |
191719016 |
G |
0.390 |
0.402 |
0.811 |
|
rs12988825 |
191722509 |
C |
0.119 |
0.132 |
0.683 |
|
rs7572482 |
191723317 |
G |
0.490 |
0.461 |
0.545 |
|
|
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|
aChromosomal positions are shown according to the National Center for Biotechnology Information (Bethesda, MD, USA) reference assembly. SLE, systemic lupus erythematosus; SNP, single nucleotide polymorphism; STAT, signal transducers and activators of transcription. |
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|
Kawasaki et al. Arthritis Research & Therapy 2008 10:R113 doi:10.1186/ar2516 |
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