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Correction

Correction: Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis

C Thomas G Appleton12, David D McErlain34, Vasek Pitelka12, Neil Schwartz5, Suzanne M Bernier16, James L Henry5, David W Holdsworth347 and Frank Beier12*

Author Affiliations

1 CIHR Group in Skeletal Development & Remodeling, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, N6A 5C1, Canada

2 Department of Physiology & Pharmacology, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, N6A 5C1, Canada

3 Imaging Research Laboratories, Robarts Research Institute, London, Ontario, N6A 5C1, Canada

4 Department of Medical Biophysics, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, N6A 5C1, Canada

5 Micheal G DeGroote Institute for Pain Research & Care, McMaster University, Hamilton, Ontario, L8S 4L8, Canada

6 Department of Anatomy & Cell Biology, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, N6A 5C1, Canada

7 Department of Diagnostic Radiology & Nuclear Medicine, Schulich School of Medicine & Dentistry, The University of Western Ontario, London, Ontario, N6A 5C1, Canada

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Arthritis Research & Therapy 2008, 10:407  doi:10.1186/ar2513


See related research by Beier et al., http://arthritis-research.com/content/9/1/R13

The electronic version of this article is the complete one and can be found online at: http://arthritis-research.com/content/10/5/407


Published:22 September 2008

© 2008 BioMed Central Ltd

Correction

After publication of our recent article [1], it has been brought to our attention that four panels in Figure 1 have been mislabeled. Images (c) and (e) are femurs, rather than tibias. Similarly, images (d) and (f) should be labelled as tibias.

As such the figure legend should read as follows:

Forced mobilization apparatus and macroscopic analysis of joint degradation. (a) Following sham (control) or OA surgery, FM animals underwent forced mobilization. Animals walked on a rotating cylinder for 30 min, three times per week. (b) FM forces the maximal extension and flexion of the knee joint (white arrow). To assess macroscopic changes to the articular surface, knee joints were dissected 4 weeks after surgery and photographed. Representative images from sham (c) femurs and (d) tibias, and ipsilateral (e) femurs and (f) tibias are shown. Surface abrasions (black arrow) and fibrotic tissue (arrow head) were observed in ipsilateral surfaces, compared with the smooth, glassy appearance in shams. Scale bar applies to panels c-f. FM, forced mobilization; OA, osteoarthritis.

References

  1. Appleton CTG, McErlain DD, Pitelka V, Schwartz N, Bernier SM, Henry JL, Holdsworth DW, Frank Beier F: Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis.

    Arthritis Res Ther 2007, 9:R13. PubMed Abstract | BioMed Central Full Text | PubMed Central Full Text OpenURL