Immunohistochemical documentation of extracellular matrix formed by sand rat adipose-derived mesenchymal stem cells in 3D culture in the presence (b, d) or absence (a, c) of transforming growth factor beta (TGFβ). Note the enhanced keratin sulphate (KS) formed when TGFβ is present (b). Chondroitin sulphate (CS) also was enhanced with TGFβ (d) compared with control (c) × 360. Immunolocalization product is brown.
Tapp et al. Arthritis Research & Therapy 2008 10:R89 doi:10.1186/ar2473