Figure 3.

The mean litter size and the frequency of litters containing dead pups in Cia40 congenic females and B10.Q wildtype littermates. (a) The mean litter size (standard error, SE) in homozygous Cia40 congenic females, heterozygous Cia40 congenic females, and wildtype B10.Q littermates (n = number of pregnancies). The difference between homozygous Cia40 congenic mice and wildtype B10.Q littermates was significant (P < 0.05). (b) The mean (SE) frequency (percentage) of litters containing dead pups in homozygous Cia40 congenic mice, heterozygous Cia40 congenic mice, and wildtype B10.Q littermates (n = number of pregnancies). The difference between Cia40 homozygous congenics and B10.Q wildtype littermates was significant (P < 0.007).