Figure 2.

Function, pain and stiffness scores. Presented are the mean scores for (a) visual analog scale, (b) Lequesne's Functional Index, (c) Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)-pain, (d) WOMAC-stiffness, and (e) WOMAC-functional ability in the low-dose (100 mg/day 5-Loxin^®) and high-dose (250 mg/day 5-Loxin^®) groups and placebo group at different time points, as indicated. Each bar represents mean concentration ± standard deviation. In comparison with placebo, the change in scores in the treatment groups was tested for significance using Tukey's multiple comparison test; asterisk indicates statistical significance.