Table 3

Haplotype frequencies and RA susceptibility

Haplotype

IL-13 haplotypes

IL-4 haplotypes


SNP1

SNP2

RA

Controls

OR (95% CI)

P

SNP3

SNP4

SNP5

RA

Controls

OR (95% CI)

P


1

C

G

0.754

0.747

1.00

-

C

G

G

0.760

0.766

1.00

-

2

T

A

0.110

0.107

1.02 (0.82–1.26)

0.86

A

G

C

0.136

0.128

0.89 (0.65 – 1.23)

0.49

3

C

A

0.065

0.078

0.83 (0.63–1.09)

0.19

A

C

G

0.090

0.091

1.38 (1.00 – 1.91)

0.96

4

T

G

0.068

0.067

1.02 (0.77–1.35)

0.91


The frequency of haplotypes in each control is shown. SNP1 is rs1800925, SNP2 is rs1295686, SNP3 is rs2227284, SNP4 is rs2243263, and SNP5 is rs2243267. CI, confidence interval; OR, odd ratio; RA, rheumatoid arthritis; SNP, single nucleotide polymorphism.

Marinou et al. Arthritis Research & Therapy 2008 10:R80   doi:10.1186/ar2454

Open Data