Figure 3.

Identification of SLRP core protein fragmentation in meniscus, knee and hip articular cartilage. Presented is identification of small leucine-rich proteoglycan (SLRP) core protein fragmentation in 4 M GuHCl extracts of meniscus, knee and hip articular cartilage of individual tissue specimens from total knee or hip replacement patients. The ages (years) of each specimen are indicated at the top of each lane. Extracts from an equivalent wet weight of tissue were loaded in each lane. The samples were pre-digested with chondroitinase ABC and keratanase-I prior to electrophoresis. Migration positions of Novex SeeBlue2 Protein standards are indicated on the left hand side of each segment.