Table 3

Significant predictors of end-stage renal disease (ESRD) in a cohort of 37 patients with lupus nephritis
Variable
 Number of ESRD patients/total number of patients
 Patient-years
 ESRD rate/1,000 patient-years
 Rate ratio
 P valuea
Tubular MT scoreb




     < 1.0
 6/16
 79
 75.9
 6.2
 0.03
     ≥ 1.0
 1/21
 82
 12.1
 1.0
Chronicity index score




     < 4
 4/30
 137
 29.2
 1
 0.04
     ≥ 4
 3/7
 24
 125
 4.2
Interstitial fibrosis




     < 2
 4/31
 143.5
 27.8
 1
 0.008
     ≥ 2
 3/6
 17.5
 171.4
 6.1

aLog-rank test. bMetallothionein score as defined in the text.

Faurschou et al. Arthritis Research & Therapy 2008 10:R76   doi:10.1186/ar2450