Diacerein inhibits the synthesis of resorptive enzymes and reduces osteoclastic differentiation/survival in osteoarthritic subchondral bone: a possible mechanism for a protective effect against subchondral bone remodelling

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Christelle Boileau, Steeve K Tat, Jean-Pierre Pelletier, Saranette Cheng and Johanne Martel-Pelletier^*

Arthritis Research & Therapy 2008, 10:R71 doi:10.1186/ar2444

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