Arthritis Research & Therapy

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Open Access Highly Access Research article

The human anti-IL-1β monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis

Rieke Alten, Hermann Gram, Leo A Joosten, Wim B Berg, Joachim Sieper, Siegfrid Wassenberg, Gerd Burmester, Piet van Riel, Maria Diaz-Lorente, Gerardus JM Bruin, Thasia G Woodworth, Christiane Rordorf, Yannik Batard, Andrew M Wright and Thomas Jung*

Arthritis Research & Therapy 2008, 10:R67 doi:10.1186/ar2438

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