Table 4

Association of the C/T polymorphism of the TXNDC3 gene with knee osteoarthritis in Chinese and Japanese populations
Groups compared
 CC versus others
 TT versus others
 All genotypesa
 C allele versus T allele


OR
 P
 95% CI
 OR
 P
 95% CI
 P
 OR
 P
 95% CI
Chinese study









All patients (n = 469) versus all controls (n = 486)
 1.31
 0.12
 0.93–1.84
 3.13
 0.14
 0.68–14.40
 0.06
 1.79
 0.26
 0.25–1.27
Female patients (n = 323) versus female controls (n = 316)
 1.28
 0.24
 0.85–1.94
 -
 -
 -
 0.04
 1.15
 0.47
 0.78–1.70
Male patients (n = 146) versus male controls (n = 170)
 1.36
 0.31
 0.75–2.45
 1.18
 0.88
 0.16–8.40
 0.55
 1.28
 0.37
 0.74–2.21
Japanese study









All patients (n = 376) versus all controls (n = 371)
 1.32
 0.11
 0.94–1.86
 0.27
 0.03
 0.08–0.88
 0.05
 1.39
 0.04
 1.02–1.89
Female patients (n = 327) versus female controls (n = 113)
 1.11
 0.68
 0.67–1.85
 0.23
 0.08
 0.04–1.22
 0.22
 1.20
 0.43
 0.76–1.89
Male patients (n = 49) versus male controls (n = 258)
 2.15
 0.07
 0.93–4.94
 0.65
 0.69
 0.08–5.26
 0.13
 2.16
 0.06
 0.96–4.84

aCC, CT and TT genotypes were grouped together, and a 2 × 3 contingency table analysis was conducted. CI, confidence interval; OR, odds ratio.

Shi et al. Arthritis Research & Therapy 2008 10:R54   doi:10.1186/ar2423