Table 3

Genotype and allele frequencies of C/T transition SNP (rs4720262) of the TXNDC3 gene in Chinese and Japanese populations

Group
Number of subjects
Genotype count (frequency)
Allele count (frequency)





CC
CT
TT
C
T

Chinese patients with knee OA
All
469
398 (0.849)
65 (0.139)
6 (0.012)
861 (0.918)
77 (0.082)
Female
323
274 (0.848)
45 (0.139)
4 (0.013)
593 (0.918)
53 (0.082)
Male
146
124 (0.849)
20 (0.137)
2 (0.014)
268 (0.918)
24 (0.082)
Chinese control individuals
All
486
394 (0.811)
90 (0.185)
2 (0.004)
878 (0.903)
94 (0.097)
Female
316
257 (0.813)
59 (0.187)
0
573 (0.907)
59 (0.093)
Male
170
137 (0.806)
31 (0.182)
2 (0.012)
305 (0.897)
35 (0.103)
Japanese patients with knee OA
All
376
299 (0.795)
74 (0.197)
3 (0.008)
672 (0.894)
80 (0.106)
Female
327
257 (0.786)
68 (0.208)
2 (0.006)
582 (0.890)
72 (0.110)
Male
49
42 (0.857)
6 (0.122)
1 (0.021)
90 (0.918)
8 (0.082)
Japanese control individuals
All
374
279 (0.746)
84 (0.225)
11 (0.029)
642 (0.858)
106 (0.142)
Female
116
89 (0.767)
24 (0.207)
3 (0.026)
202 (0.871)
30 (0.129)
Male
258
190 (0.736)
60 (0.233)
8 (0.031)
440 (0.853)
76 (0.147)

OA, osteoarthritis; SNP, single nucleotide polymorphism.

Shi et al. Arthritis Research & Therapy 2008 10:R54   doi:10.1186/ar2423