|
Association of the A/G polymorphism of the RHOB gene with knee osteoarthritis in Chinese and Japanese populations |
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| Groups compared |
AA versus AG |
A allele versus G allele |
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|
|
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| OR |
P |
95% CI |
OR |
P |
95% CI |
|
|
|
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| Chinese study |
||||||
| All patients (n = 469) versus all controls (n = 486) |
0.70 |
0.18 |
0.42–1.18 |
0.71 |
0.19 |
0.42–1.18 |
| Female patients (n = 323) versus female controls (n = 316) |
1.02 |
0.94 |
0.54–1.94 |
1.02 |
0.94 |
0.54–1.92 |
| Male patients (n = 146) versus male controls (n = 170) |
0.32 |
0.02 |
0.12–0.85 |
0.32 |
0.02 |
0.12–0.85 |
| Japanese study |
||||||
| All patients (n = 376) versus all controls (n = 371) |
1.10 |
0.74 |
0.63–1.91 |
1.10 |
0.74 |
0.64–1.89 |
| Female patients (n = 327) versus female controls (n = 113) |
1.23 |
0.60 |
0.57–2.65 |
1.22 |
0.61 |
0.57–2.58 |
| Male patients (n = 49) versus male controls (n = 258) |
1.76 |
0.45 |
0.40–7.85 |
1.67 |
0.46 |
0.40–7.85 |
|
CI, confidence interval; OR, odds ratio. | ||||||
Shi et al. Arthritis Research & Therapy 2008 10:R54 doi:10.1186/ar2423 |
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