Research article
Discontinuation rates in clinical trials in musculoskeletal pain: meta-analysis from etoricoxib clinical trial reports
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* Corresponding author: R Andrew Moore andrew.moore@pru.ox.ac.uk
Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, The Churchill, Oxford OX3 7LJ, UK
Arthritis Research & Therapy 2008, 10:R53 doi:10.1186/ar2422
Published: 8 May 2008Additional files
Additional file 1:
Details of the randomized trials included in the review. The file contains information on each included study, with reference, quality score, design, treatments, main results and comments.
Format: PDF Size: 57KB Download file
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Additional file 2:
Discontinuation rates over 12 weeks because of lack of efficacy in trials conducted over 4 to 12 weeks. The file contains information on percentage of patients not discontinued because of lack of efficacy for weeks 1 to 12, by treatment.
Format: PDF Size: 22KB Download file
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Additional file 3:
Discontinuation rates over 12 weeks because of adverse events in trials conducted over 4 to 12 weeks. The file contains information on percentage of patients not discontinued because of adverse events for weeks 1 to 12, by treatment.
Format: PDF Size: 22KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional file 4:
Comparison between meta-analyses of etoricoxib, valdecoxib, and celecoxib trials. The file contains information on percentage of patients discontinued by end of trial in meta-analyses of etoricoxib, valdecoxib, and celecoxib trials.
Format: PDF Size: 27KB Download file
This file can be viewed with: Adobe Acrobat Reader