Table 3

Correlations with clinical and laboratory parameters of anti-CCP antibody-positive and -negative primary Sjögren syndrome patients


Anti-CCP-positive (n = 14)
Anti-CCP-negative (n = 127)
P value

Age (range), years
41 (34.5–52.2)
49 (39–60)
0.134
Disease duration, years
2.4 (1.40–7.5)
2.5 (0.98–5.2)
0.415
Synovitis, number (percentage)
12 (85.7)
32 (25.2)
<0.001
Extra-glandular involvement, number (percentage)
9 (64.3)
72 (56.7)
0.777
Erythrocyte sedimentation rate (range), mm/1st hour
34 (24.25–45.5)
27 (16.5–38)
0.101
Rheumatoid factor, number (percentage)
10 (71.4)
84 (66.1)
0.774
Anti-nuclear antibodies, number (percentage)
13 (92.9)
121 (95.3)
0.527
Anti-La (SSB) antibodies, number (percentage)
10 (71.4)
105 (82.7)
0.291
Anti-Ro (SSA) antibodies, number (percentage)
6 (42.9)
49 (38.6)
0.779
Focus score of greater than 1, number (percentage)
9 (64.3)
85 (67.5)
0.773

Anti-CCP, cyclic citrullinated peptide antibody.

Atzeni et al. Arthritis Research & Therapy 2008 10:R51   doi:10.1186/ar2420