|
Gene expression analysis by real-time quantitative RT-PCR |
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| Gene |
Responder |
Nonresponder |
P value |
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|
|
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| NFKBIA |
-0.227 |
(± 0.749) |
1.053 |
(± 1.128) |
0.008 |
| CCL4 |
-0.142 |
(± 1.184) |
1.144 |
(± 0.924) |
0.025 |
| IL8 |
-0.025 |
(± 1.871) |
2.429 |
(± 2.489) |
0.028 |
| IL1B |
-0.595 |
(± 1.680) |
1.487 |
(± 2.191) |
0.032 |
| TNFAIP3 |
0.002 |
(± 0.895) |
1.266 |
(± 1.510) |
0.034 |
| PDE4B |
-0.276 |
(± 0.846) |
0.534 |
(± 0.544) |
0.037 |
| PPP1R15A |
-0.280 |
(± 0.935) |
0.825 |
(± 1.225) |
0.040 |
| ADM |
-0.931 |
(± 1.289) |
0.279 |
(± 1.016) |
0.049 |
|
Data shown are the changes of gene expression (-ΔΔCT t1 versus t0; mean ± standard deviation) of eight selected genes averaged over the 12 responders and seven nonresponders, and the corresponding P values determined by two-sample t test comparing the means of responders and nonresponders. | |||||
Koczan et al. Arthritis Research & Therapy 2008 10:R50 doi:10.1186/ar2419 |
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