Figure 5.

Effect of disease-modifying antirheumatic drug therapy. Disease-modifying antirheumatic drugs (DMARDs) will interfere with the disease process at any time point, and will lead to a deflection of the slope of progression from its natural course. The ideal situation would be to diagnose and treat rheumatoid arthritis early; at best, before damage has occurred.

Smolen et al. Arthritis Research & Therapy 2008 10:208   doi:10.1186/ar2418
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