Table 1 |
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Comparison of definitions of metabolic syndrome |
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| World Health Organization |
National Cholesterol Education Program |
International Diabetes Federation |
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| Diabetes or impaired fasting glycemia orimpaired glucose tolerance or insulin resistance
(hyperinsulinemic, euglycemic clamp-glucose uptake in lowest 25%) |
Central obesity: waist circumference ≥ 94 cm (male) or ≥ 80 cm (female)a, or ≥ 90 cm (male) or ≥ 80 cm (female)b |
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| Plus two or more of the following |
Three or more of the following |
Plus two or more of the following |
| Obesity: body mass index >30 or waist-to-hip ratio >0.9 (male) or >0.85 (female) |
Central obesity: waist circumference >102 cm (male) or >88 cm (female) |
Fasting plasma glucose ≥ 5.6 mmol/L or medication |
| Dyslipidemia: triglycerides ≥ 1.7 mmol/L or HDL cholesterol <0.9 mmol/L (male) or
<1.0 mmol/L (female) |
Hypertriglyceridemia: triglycerides ≥ 1.7 mmol/L |
Hypertriglyceridemia: triglycerides ≥ 1.7 mmol/L or medication |
| Hypertension: blood pressure ≥ 140/90 mm Hg |
Low HDL cholesterol: <1.0 mmol/L (male)or <1.3 mmol/L (female) |
Low HDL cholesterol: <1.0 mmol/L (male) or <1.3 mmol/L (female) or medication |
| Microalbuminuria: albumin excretion >20 μg/minute |
Hypertension: blood pressure ≥ 130/85 mm Hg |
Hypertension: blood pressure ≥ 130/85 mm Hg or medication |
| Fasting plasma glucose ≥ 6.1 mmol/L |
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aEuropeans, Sub-Saharan Africans, and Eastern Mediterranean and Middle East (Arab) populations; bSouth Asians and Ethnic South and Central Americans. HDL, high-density lipoprotein. |
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Sidiropoulos et al. Arthritis Research & Therapy 2008 10:207 doi:10.1186/ar2397 |
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