Arthritis Research & Therapy | Volume 10 Issue 3

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	Volume 10 Issue 3
	Comment
	Editorial The relationship between cancer and rheumatoid arthritis: still a large research agenda Thorvardur Love, Daniel H Solomon Arthritis Research & Therapy 2008, 10:109 (14 May 2008) Abstract \| Full text \| PDF \| PubMed
	Editorial High mobility group box-1 protein as a tumor necrosis factor-independent therapeutic target in rheumatoid arthritis Richard S Goldstein Arthritis Research & Therapy 2008, 10:111 (2 June 2008) Abstract \| Full text \| PDF \| PubMed
	Editorial Gout in the spotlight Alexander So Arthritis Research & Therapy 2008, 10:112 (6 June 2008) Abstract \| Full text \| PDF \| PubMed
	Editorial Paradoxical effects of tumour necrosis factor-α in adjuvant-induced arthritis Richard O Williams Arthritis Research & Therapy 2008, 10:113 (6 June 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary Arthritis gene therapy's first death Christopher H Evans, Steven C Ghivizzani, Paul D Robbins Arthritis Research & Therapy 2008, 10:110 (27 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review
	Review Metabolic syndrome in rheumatic diseases: epidemiology, pathophysiology, and clinical implications Prodromos I Sidiropoulos, Stylianos A Karvounaris, Dimitrios T Boumpas Arthritis Research & Therapy 2008, 10:207 (8 May 2008) Abstract \| Full text \| PDF \| PubMed
	Review The need for prognosticators in rheumatoid arthritis. Biological and clinical markers: where are we now? Josef S Smolen, Daniel Aletaha, Johannes Grisar, Kurt Redlich, Günter Steiner, Oswald Wagner Arthritis Research & Therapy 2008, 10:208 (29 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review High-mobility group box protein 1 (HMGB1): an alarmin mediating the pathogenesis of rheumatic disease David S Pisetsky, Helena Erlandsson-Harris, Ulf Andersson Arthritis Research & Therapy 2008, 10:209 (30 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research
	Research article Molecular discrimination of responders and nonresponders to anti-TNFalpha therapy in rheumatoid arthritis by etanercept Dirk Koczan, Susanne Drynda, Michael Hecker, Andreas Drynda, Reinhard Guthke, Joern Kekow, Hans-Juergen Thiesen Arthritis Research & Therapy 2008, 10:R50 (2 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Anti-cyclic citrullinated peptide antibodies in primary Sjögren syndrome may be associated with non-erosive synovitis Fabiola Atzeni, Piercarlo Sarzi-Puttini, Nicola Lama, Eleonora Bonacci, Francesca Bobbio-Pallavicini, Carlomaurizio Montecucco, Roberto Caporali Arthritis Research & Therapy 2008, 10:R51 (7 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Genetic polymorphisms in PTPN22, PADI-4, and CTLA-4 and risk for rheumatoid arthritis in two longitudinal cohort studies: evidence of gene-environment interactions with heavy cigarette smoking Karen H Costenbader, Shun-Chiao Chang, Immaculata De Vivo, Robert Plenge, Elizabeth W Karlson Arthritis Research & Therapy 2008, 10:R52 (7 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Analysis of data from a study of American nurses confirms the PTPN22 polymorphism is a strong risk factor for rheumatoid arthritis, and that its presence interacts multiplicatively with heavy smoking.
	Research article Discontinuation rates in clinical trials in musculoskeletal pain: meta-analysis from etoricoxib clinical trial reports R Andrew Moore, Sheena Derry, Henry J McQuay Arthritis Research & Therapy 2008, 10:R53 (8 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Association of single-nucleotide polymorphisms in RHOB and TXNDC3 with knee osteoarthritis susceptibility: two case-control studies in East Asian populations and a meta-analysis Dongquan Shi, Takahiro Nakamura, Masahiro Nakajima, Jin Dai, Jianghui Qin, Haijian Ni, Yong Xu, Chen Yao, Jia Wei, Baorui Liu, Shiro Ikegawa, Qing Jiang Arthritis Research & Therapy 2008, 10:R54 (10 May 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Characteristics of T-cell large granular lymphocyte proliferations associated with neutropenia and inflammatory arthropathy Monika Prochorec-Sobieszek, Grzegorz Rymkiewicz, Hanna Makuch-Łasica, Mirosław Majewski, Katarzyna Michalak, Robert Rupiński, Krzysztof Warzocha, Renata Maryniak Arthritis Research & Therapy 2008, 10:R55 (12 May 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Sleep structure and sleepiness in chronic fatigue syndrome with or without coexisting fibromyalgia Fumiharu Togo, Benjamin H Natelson, Neil S Cherniack, Jennifer FitzGibbons, Carmen Garcon, David M Rapoport Arthritis Research & Therapy 2008, 10:R56 (13 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Leukocyte numbers and function in subjects eating n-3 enriched foods: selective depression of natural killer cell levels Violet R Mukaro, Maurizio Costabile, Karen J Murphy, Charles S Hii, Peter R Howe, Antonio Ferrante Arthritis Research & Therapy 2008, 10:R57 (14 May 2008) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Regular long-term consumption of omega-3 enriched foods leads to reduced natural killer cell levels, providing a rationale for the decreased inflammatory reaction seen in arthritis patients receiving this dietary supplementation.
	Research article Association between meniscal tears and the peak external knee adduction moment and foot rotation during level walking in postmenopausal women without knee osteoarthritis: a cross-sectional study Miranda L Davies-Tuck, Anita E Wluka, Andrew J Teichtahl, Johanne Martel-Pelletier, Jean-Pierre Pelletier, Graeme Jones, Changhai Ding, Susan R Davis, Flavia M Cicuttini Arthritis Research & Therapy 2008, 10:R58 (20 May 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Cigarette smoking associates with body weight and muscle mass of patients with rheumatoid arthritis: a cross-sectional, observational study Antonios Stavropoulos-Kalinoglou, Giorgos S Metsios, Vasileios F Panoulas, Karen MJ Douglas, Alan M Nevill, Athanasios Z Jamurtas, Marina Kita, Yiannis Koutedakis, George D Kitas Arthritis Research & Therapy 2008, 10:R59 (20 May 2008) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Smoking cessation programmes for rheumatoid arthritis patients should include counselling on weight control, as quitting appears to be associated with an increase in body mass index, an observational study has found.
	Research article DREAM is reduced in synovial fibroblasts of patients with chronic arthritic pain: is it a suitable target for peripheral pain management? Nataša Reisch, Andrea Engler, André Aeschlimann, Beat R Simmen, Beat A Michel, Renate E Gay, Steffen Gay, Haiko Sprott Arthritis Research & Therapy 2008, 10:R60 (28 May 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage Shuhei Otsuki, Noboru Taniguchi, Shawn P Grogan, Darryl D'Lima, Mitsuo Kinoshita, Martin Lotz Arthritis Research & Therapy 2008, 10:R61 (28 May 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Leg-length inequality is not associated with greater trochanteric pain syndrome Neil A Segal, William Harvey, David T Felson, Mei Yang, James C Torner, Jeffrey R Curtis, Michael C Nevitt, the Multicenter Osteoarthritis Study Group Arthritis Research & Therapy 2008, 10:R62 (29 May 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity Morten A Karsdal, Suzi H Madsen, Claus Christiansen, Kim Henriksen, Amanda J Fosang, Bodil C Sondergaard Arthritis Research & Therapy 2008, 10:R63 (30 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research article Identification of novel monosodium urate crystal regulated mRNAs by transcript profiling of dissected murine air pouch membranes Frank Pessler, Christian T Mayer, Sung Jung, Ed M Behrens, Lie Dai, Joseph P Menetski, H Ralph Schumacher Arthritis Research & Therapy 2008, 10:R64 (3 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Several genes that may be part of a "second wave" of factors amplifying or perpetuating acute inflammation have been identified in a study of monosodium urate crystal-induced inflammation in mice.
	Research article Chordin knockdown enhances the osteogenic differentiation of human mesenchymal stem cells Francois NK Kwong, Stephen M Richardson, Christopher H Evans Arthritis Research & Therapy 2008, 10:R65 (4 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Therapeutic effects of antibodies to tumor necrosis factor-α, interleukin-6 and cytotoxic T-lymphocyte antigen 4 immunoglobulin in mice with glucose-6-phosphate isomerase induced arthritis Isao Matsumoto, Hua Zhang, Takanori Yasukochi, Keiichi Iwanami, Yoko Tanaka, Asuka Inoue, Daisuke Goto, Satoshi Ito, Akito Tsutsumi, Takayuki Sumida Arthritis Research & Therapy 2008, 10:R66 (5 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article The human anti-IL-1β monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis Rieke Alten, Hermann Gram, Leo A Joosten, Wim Berg, Joachim Sieper, Siegfrid Wassenberg, Gerd Burmester, Piet van Riel, Maria Diaz-Lorente, Gerardus JM Bruin, Thasia G Woodworth, Christiane Rordorf, Yannik Batard, Andrew M Wright, Thomas Jung Arthritis Research & Therapy 2008, 10:R67 (5 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A novel human monoclonal antibody directed against interleukin 1-beta, ACZ885, was well tolerated and effective in half of those rheumatoid arthritis patients treated in a first in man, proof of concept study.
	Research article The 5.5-year results of MegaOATS – autologous transfer of the posterior femoral condyle: a case-series study Sepp Braun, Philipp Minzlaff, Regina Hollweck, Klaus Wörtler, Andreas B Imhoff Arthritis Research & Therapy 2008, 10:R68 (16 June 2008) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Young patients who undergo autologous transfer of the posterior femoral condyle to treat lesions of the knee show significant improvements in daily life activity levels, with many returning to recreational sports.
	Research article Altered fractalkine cleavage potentially promotes local inflammation in NOD salivary gland Manon E Wildenberg, Cornelia G van Helden-Meeuwsen, Hemmo A Drexhage, Marjan A Versnel Arthritis Research & Therapy 2008, 10:R69 (19 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article The association between disease activity and NT-proBNP in 238 patients with rheumatoid arthritis: a 10-year longitudinal study Sella A Provan, Kristin Angel, Sigrid Ødegård, Petter Mowinckel, Dan Atar, Tore K Kvien Arthritis Research & Therapy 2008, 10:R70 (23 June 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Diacerein inhibits the synthesis of resorptive enzymes and reduces osteoclastic differentiation/survival in osteoarthritic subchondral bone: a possible mechanism for a protective effect against subchondral bone remodelling Christelle Boileau, Steeve Tat, Jean-Pierre Pelletier, Saranette Cheng, Johanne Martel-Pelletier Arthritis Research & Therapy 2008, 10:R71 (25 June 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Induction of arthritis by high mobility group box chromosomal protein 1 is independent of tumour necrosis factor signalling Rille Pullerits, Ing-Marie Jonsson, George Kollias, Andrej Tarkowski Arthritis Research & Therapy 2008, 10:R72 (26 June 2008) Abstract \| Full text \| PDF \| PubMed
	Correspondence
	Letter Carotid intima-media thickness and endothelial function: useful surrogate markers for establishing cardiovascular risk in patients with inflammatory rheumatic disease Miguel A Gonzalez-Gay, Carlos Gonzalez-Juanatey, Tomas R Vazquez-Rodriguez, Javier Martin, Javier Llorca Arthritis Research & Therapy 2008, 10:403 (16 May 2008) Abstract \| Full text \| PDF \| PubMed
	Letter Carotid intima-media thickness and endothelial function: useful surrogate markers for establishing cardiovascular risk in patients with inflammatory rheumatic disease – authors' response Jet van Zanten, George D Kitas Arthritis Research & Therapy 2008, 10:404 (16 May 2008) Abstract \| Full text \| PDF \| PubMed

	Volume 10 Issue 3
	Comment
	Editorial The relationship between cancer and rheumatoid arthritis: still a large research agenda Thorvardur Love, Daniel H Solomon Arthritis Research & Therapy 2008, 10:109 (14 May 2008) Abstract \| Full text \| PDF \| PubMed
	Editorial High mobility group box-1 protein as a tumor necrosis factor-independent therapeutic target in rheumatoid arthritis Richard S Goldstein Arthritis Research & Therapy 2008, 10:111 (2 June 2008) Abstract \| Full text \| PDF \| PubMed
	Editorial Gout in the spotlight Alexander So Arthritis Research & Therapy 2008, 10:112 (6 June 2008) Abstract \| Full text \| PDF \| PubMed
	Editorial Paradoxical effects of tumour necrosis factor-α in adjuvant-induced arthritis Richard O Williams Arthritis Research & Therapy 2008, 10:113 (6 June 2008) Abstract \| Full text \| PDF \| PubMed
	Commentary Arthritis gene therapy's first death Christopher H Evans, Steven C Ghivizzani, Paul D Robbins Arthritis Research & Therapy 2008, 10:110 (27 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review
	Review Metabolic syndrome in rheumatic diseases: epidemiology, pathophysiology, and clinical implications Prodromos I Sidiropoulos, Stylianos A Karvounaris, Dimitrios T Boumpas Arthritis Research & Therapy 2008, 10:207 (8 May 2008) Abstract \| Full text \| PDF \| PubMed
	Review The need for prognosticators in rheumatoid arthritis. Biological and clinical markers: where are we now? Josef S Smolen, Daniel Aletaha, Johannes Grisar, Kurt Redlich, Günter Steiner, Oswald Wagner Arthritis Research & Therapy 2008, 10:208 (29 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review High-mobility group box protein 1 (HMGB1): an alarmin mediating the pathogenesis of rheumatic disease David S Pisetsky, Helena Erlandsson-Harris, Ulf Andersson Arthritis Research & Therapy 2008, 10:209 (30 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research
	Research article Molecular discrimination of responders and nonresponders to anti-TNFalpha therapy in rheumatoid arthritis by etanercept Dirk Koczan, Susanne Drynda, Michael Hecker, Andreas Drynda, Reinhard Guthke, Joern Kekow, Hans-Juergen Thiesen Arthritis Research & Therapy 2008, 10:R50 (2 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Anti-cyclic citrullinated peptide antibodies in primary Sjögren syndrome may be associated with non-erosive synovitis Fabiola Atzeni, Piercarlo Sarzi-Puttini, Nicola Lama, Eleonora Bonacci, Francesca Bobbio-Pallavicini, Carlomaurizio Montecucco, Roberto Caporali Arthritis Research & Therapy 2008, 10:R51 (7 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Genetic polymorphisms in PTPN22, PADI-4, and CTLA-4 and risk for rheumatoid arthritis in two longitudinal cohort studies: evidence of gene-environment interactions with heavy cigarette smoking Karen H Costenbader, Shun-Chiao Chang, Immaculata De Vivo, Robert Plenge, Elizabeth W Karlson Arthritis Research & Therapy 2008, 10:R52 (7 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Analysis of data from a study of American nurses confirms the PTPN22 polymorphism is a strong risk factor for rheumatoid arthritis, and that its presence interacts multiplicatively with heavy smoking.
	Research article Discontinuation rates in clinical trials in musculoskeletal pain: meta-analysis from etoricoxib clinical trial reports R Andrew Moore, Sheena Derry, Henry J McQuay Arthritis Research & Therapy 2008, 10:R53 (8 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Association of single-nucleotide polymorphisms in RHOB and TXNDC3 with knee osteoarthritis susceptibility: two case-control studies in East Asian populations and a meta-analysis Dongquan Shi, Takahiro Nakamura, Masahiro Nakajima, Jin Dai, Jianghui Qin, Haijian Ni, Yong Xu, Chen Yao, Jia Wei, Baorui Liu, Shiro Ikegawa, Qing Jiang Arthritis Research & Therapy 2008, 10:R54 (10 May 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Characteristics of T-cell large granular lymphocyte proliferations associated with neutropenia and inflammatory arthropathy Monika Prochorec-Sobieszek, Grzegorz Rymkiewicz, Hanna Makuch-Łasica, Mirosław Majewski, Katarzyna Michalak, Robert Rupiński, Krzysztof Warzocha, Renata Maryniak Arthritis Research & Therapy 2008, 10:R55 (12 May 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Sleep structure and sleepiness in chronic fatigue syndrome with or without coexisting fibromyalgia Fumiharu Togo, Benjamin H Natelson, Neil S Cherniack, Jennifer FitzGibbons, Carmen Garcon, David M Rapoport Arthritis Research & Therapy 2008, 10:R56 (13 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Leukocyte numbers and function in subjects eating n-3 enriched foods: selective depression of natural killer cell levels Violet R Mukaro, Maurizio Costabile, Karen J Murphy, Charles S Hii, Peter R Howe, Antonio Ferrante Arthritis Research & Therapy 2008, 10:R57 (14 May 2008) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Regular long-term consumption of omega-3 enriched foods leads to reduced natural killer cell levels, providing a rationale for the decreased inflammatory reaction seen in arthritis patients receiving this dietary supplementation.
	Research article Association between meniscal tears and the peak external knee adduction moment and foot rotation during level walking in postmenopausal women without knee osteoarthritis: a cross-sectional study Miranda L Davies-Tuck, Anita E Wluka, Andrew J Teichtahl, Johanne Martel-Pelletier, Jean-Pierre Pelletier, Graeme Jones, Changhai Ding, Susan R Davis, Flavia M Cicuttini Arthritis Research & Therapy 2008, 10:R58 (20 May 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Cigarette smoking associates with body weight and muscle mass of patients with rheumatoid arthritis: a cross-sectional, observational study Antonios Stavropoulos-Kalinoglou, Giorgos S Metsios, Vasileios F Panoulas, Karen MJ Douglas, Alan M Nevill, Athanasios Z Jamurtas, Marina Kita, Yiannis Koutedakis, George D Kitas Arthritis Research & Therapy 2008, 10:R59 (20 May 2008) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Smoking cessation programmes for rheumatoid arthritis patients should include counselling on weight control, as quitting appears to be associated with an increase in body mass index, an observational study has found.
	Research article DREAM is reduced in synovial fibroblasts of patients with chronic arthritic pain: is it a suitable target for peripheral pain management? Nataša Reisch, Andrea Engler, André Aeschlimann, Beat R Simmen, Beat A Michel, Renate E Gay, Steffen Gay, Haiko Sprott Arthritis Research & Therapy 2008, 10:R60 (28 May 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Expression of novel extracellular sulfatases Sulf-1 and Sulf-2 in normal and osteoarthritic articular cartilage Shuhei Otsuki, Noboru Taniguchi, Shawn P Grogan, Darryl D'Lima, Mitsuo Kinoshita, Martin Lotz Arthritis Research & Therapy 2008, 10:R61 (28 May 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Leg-length inequality is not associated with greater trochanteric pain syndrome Neil A Segal, William Harvey, David T Felson, Mei Yang, James C Torner, Jeffrey R Curtis, Michael C Nevitt, the Multicenter Osteoarthritis Study Group Arthritis Research & Therapy 2008, 10:R62 (29 May 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity Morten A Karsdal, Suzi H Madsen, Claus Christiansen, Kim Henriksen, Amanda J Fosang, Bodil C Sondergaard Arthritis Research & Therapy 2008, 10:R63 (30 May 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
	Research article Identification of novel monosodium urate crystal regulated mRNAs by transcript profiling of dissected murine air pouch membranes Frank Pessler, Christian T Mayer, Sung Jung, Ed M Behrens, Lie Dai, Joseph P Menetski, H Ralph Schumacher Arthritis Research & Therapy 2008, 10:R64 (3 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Several genes that may be part of a "second wave" of factors amplifying or perpetuating acute inflammation have been identified in a study of monosodium urate crystal-induced inflammation in mice.
	Research article Chordin knockdown enhances the osteogenic differentiation of human mesenchymal stem cells Francois NK Kwong, Stephen M Richardson, Christopher H Evans Arthritis Research & Therapy 2008, 10:R65 (4 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Therapeutic effects of antibodies to tumor necrosis factor-α, interleukin-6 and cytotoxic T-lymphocyte antigen 4 immunoglobulin in mice with glucose-6-phosphate isomerase induced arthritis Isao Matsumoto, Hua Zhang, Takanori Yasukochi, Keiichi Iwanami, Yoko Tanaka, Asuka Inoue, Daisuke Goto, Satoshi Ito, Akito Tsutsumi, Takayuki Sumida Arthritis Research & Therapy 2008, 10:R66 (5 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article The human anti-IL-1β monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis Rieke Alten, Hermann Gram, Leo A Joosten, Wim Berg, Joachim Sieper, Siegfrid Wassenberg, Gerd Burmester, Piet van Riel, Maria Diaz-Lorente, Gerardus JM Bruin, Thasia G Woodworth, Christiane Rordorf, Yannik Batard, Andrew M Wright, Thomas Jung Arthritis Research & Therapy 2008, 10:R67 (5 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A novel human monoclonal antibody directed against interleukin 1-beta, ACZ885, was well tolerated and effective in half of those rheumatoid arthritis patients treated in a first in man, proof of concept study.
	Research article The 5.5-year results of MegaOATS – autologous transfer of the posterior femoral condyle: a case-series study Sepp Braun, Philipp Minzlaff, Regina Hollweck, Klaus Wörtler, Andreas B Imhoff Arthritis Research & Therapy 2008, 10:R68 (16 June 2008) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Young patients who undergo autologous transfer of the posterior femoral condyle to treat lesions of the knee show significant improvements in daily life activity levels, with many returning to recreational sports.
	Research article Altered fractalkine cleavage potentially promotes local inflammation in NOD salivary gland Manon E Wildenberg, Cornelia G van Helden-Meeuwsen, Hemmo A Drexhage, Marjan A Versnel Arthritis Research & Therapy 2008, 10:R69 (19 June 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article The association between disease activity and NT-proBNP in 238 patients with rheumatoid arthritis: a 10-year longitudinal study Sella A Provan, Kristin Angel, Sigrid Ødegård, Petter Mowinckel, Dan Atar, Tore K Kvien Arthritis Research & Therapy 2008, 10:R70 (23 June 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Diacerein inhibits the synthesis of resorptive enzymes and reduces osteoclastic differentiation/survival in osteoarthritic subchondral bone: a possible mechanism for a protective effect against subchondral bone remodelling Christelle Boileau, Steeve Tat, Jean-Pierre Pelletier, Saranette Cheng, Johanne Martel-Pelletier Arthritis Research & Therapy 2008, 10:R71 (25 June 2008) Abstract \| Full text \| PDF \| PubMed
	Research article Induction of arthritis by high mobility group box chromosomal protein 1 is independent of tumour necrosis factor signalling Rille Pullerits, Ing-Marie Jonsson, George Kollias, Andrej Tarkowski Arthritis Research & Therapy 2008, 10:R72 (26 June 2008) Abstract \| Full text \| PDF \| PubMed
	Correspondence
	Letter Carotid intima-media thickness and endothelial function: useful surrogate markers for establishing cardiovascular risk in patients with inflammatory rheumatic disease Miguel A Gonzalez-Gay, Carlos Gonzalez-Juanatey, Tomas R Vazquez-Rodriguez, Javier Martin, Javier Llorca Arthritis Research & Therapy 2008, 10:403 (16 May 2008) Abstract \| Full text \| PDF \| PubMed
	Letter Carotid intima-media thickness and endothelial function: useful surrogate markers for establishing cardiovascular risk in patients with inflammatory rheumatic disease – authors' response Jet van Zanten, George D Kitas Arthritis Research & Therapy 2008, 10:404 (16 May 2008) Abstract \| Full text \| PDF \| PubMed

Explore journal

Articles

Volume 10 Issue 3

Comment

Review

Research

Correspondence