Table 1

Plasma IL-6 levels after soluble tissue factor injection

Untreated mice

Soluble tissue factor wildtype mice

No treatment

ASIS treatment

Hirudin treatment

Ancrod treatment

n

6

33

5

5

5

Mean (pg/ml)

<2

285

6.3

<2

<2

Standard error of the mean

107

6

Plasma was collected 24 hours after soluble tissue factor footpad injection. In a parallel experiment, plasma was also collected from noninjected, naïve control mice. ASIS, active site inhibited activated factor VII.

Busso et al. Arthritis Research & Therapy 2008 10:R42   doi:10.1186/ar2400