Table 2

Relationship between day 8 Tck phenotype (MFI) and effector function (TNF-α production from co-cultured monocytes)

Cell phenotype
n
r (correlation)
P

CD25
40
-0.2558
NS
CD69
41
0.00053
NS
HLA-DR
15
0.4094
NS
CD62L
31
-0.4652
0.00084
CD18
21
0.1442
NS
CD29
35
0.2167
NS
CD49d
42
0.3314
0.032
CCR7
42
-0.1711
NS
CXCR4
21
-0.13
NS
CXCR3
21
0.02341
NS
CCR5
21
-0.3948
NS

Day 8 expression of cell surface markers (mean fluorescence intensity [MFI]) was correlated with effector function (tumour necrosis factor [TNF]-α production from monocytes in cytokine-activated T [Tck] cell:monocyte co-culture) using nonparametric (Spearman) correlation analysis. Results are expressed as correlation values (r) and level of significance.

Brennan et al. Arthritis Research & Therapy 2008 10:R36   doi:10.1186/ar2390