Table 2 |
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|
Disease activity and lipid variables for the patients who followed the diet regimens for at least 3 months |
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|
Vegan diet patients |
Non-vegan diet patients |
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|
|
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|
Baseline |
3 months |
P value |
12 months |
P value |
Baseline |
3 months |
P value |
12 months |
P value |
|
|
|
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|
DAS28a |
5.3 (5.0–5.7) |
4.7 (4.3–5.2) |
0.002 |
4.3 (3.8–4.9) |
<0.001 |
5.3 (4.9–5.6) |
5.0 (4.6–5.3) |
0.014 |
5.0 (4.6–5.4) |
0.19 |
|
HAQ scorea |
1.4 (1.2–1.5) |
1.1 (0.9–1.3) |
0.010 |
1.0 (0.8–1.2) |
0.001 |
1.3 (1.1–1.5) |
1.2 (1.0–1.4) |
0.62 |
1.2 (1.0–1.4) |
0.59 |
|
CRPb |
13 (6–26) |
11 (5–29) |
0.68 |
5 (4–20) |
0.008 |
22 (5–32) |
10 (5–33) |
0.07 |
12 (4–19) |
0.28 |
|
Albumina |
36 (34–37) |
34 (33–35) |
0.013 |
36 (35–38) |
0.43 |
35 (34–37) |
37 (35–39) |
0.06 |
37 (35–38) |
0.06 |
|
Cholesterolb |
5.2 (4.4–5.7) |
4.3 (3.9–5.0) |
<0.001 |
4.3 (3.8–5.1) |
0.003 |
4.7 (4.2–5.3) |
5.1 (4.3–5.5) |
0.20 |
5.0 (4.0–5.5) |
0.68 |
|
Triglyceridesa |
1.1 (1.0–1.3) |
1.2 (1.0–1.3) |
0.43 |
1.1 (0.9–1.2) |
0.32 |
1.1 (0.9–1.5) |
1.2 (0.7–1.6) |
0.79 |
1.1 (0.8–1.3) |
0.69 |
|
HDLa |
1.4 (1.3–1.5) |
1.3 (1.2–1.4) |
0.14 |
1.4 (1.3–1.6) |
0.22 |
1.3 (1.2–1.3) |
1.3 (1.2–1.4) |
0.045 |
1.3 (1.2–1.4) |
0.07 |
|
LDLb |
3.2 (2.6–3.7) |
1.3 (1.2–1.6) |
<0.001 |
2.4 (2.1–3.0) |
<0.001 |
2.9 (2.5–3.4) |
3.1 (1.2–1.5) |
0.23 |
3.2 (2.4–3.5) |
0.83 |
|
LDL/HDLa |
2.7 (2.2–3.1) |
2.0 (1.8–2.3) |
<0.001 |
1.9 (1.6–2.2) |
<0.001 |
2.4 (2.2–2.7) |
2.5 (2.2–2.7) |
1.00 |
2.2 (2.0–2.5) |
0.22 |
|
oxLDLa |
54.7 (46.2–63.2) |
49.4 (43.0–55.8) |
0.021 |
48.6 (41.7–56.5) |
0.09 |
54.5 (45.9–63.1) |
54.8 (46.2–63.4) |
0.88 |
55.2 (45.6–64.7) |
0.57 |
|
anti-PC, IgMa |
778 (706–849) |
812 (729–896) |
0.39 |
822 (743–900) |
0.057 |
797 (676–918) |
742 (620–864) |
<0.001 |
731 (596–870) |
0.003 |
|
anti-PC, IgGa |
861 (761–962) |
879 (785–974) |
0.28 |
859 (760–957) |
0.92 |
913 (814–1012) |
900 (802–999) |
0.46 |
880 (764–996) |
0.47 |
|
anti-PC, IgAa |
837 (588–1087) |
938 (640–1234) |
0.027 |
854 (595–1112) |
0.26 0.62 |
798 (567–1030) |
772 (539–1005) |
0.17 |
745 (357–1028) |
0.42 |
|
|
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|
aMean values (confidence interval 95%). bMedian values (25th to 75th percentile). P values are differences between baseline and 3 and 12 months, respectively, for each diet group. Anti-PC, antibody against phosphorylcholine; CRP, C-reactive protein; DAS28, Disease Activity Score in 28 joints; HAQ, Health Assessment Questionnaire; HDL, high-density lipoprotein; LDL, low-density lipoprotein; oxLDL, oxidized low-density lipoprotein. |
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|
Elkan et al. Arthritis Research & Therapy 2008 10:R34 doi:10.1186/ar2388 |
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