Table 3

Univariate analyses for cardiovascular morbidity in patients with rheumatoid arthritis in the QUEST-RA study

Cardiovascular morbidity (percentage of patients)


No

Yes

Hazard ratio

95% CI

P value


Rheumatoid variables

Rheumatoid factor

71.7

77.0

1.02

0.76–1.37

0.881

Extra-articular diseasea

23.0

43.3

1.52

1.19–1.95

0.001

Traditional risk factors

Age in years (mean)

55.8

66.4

1.05

1.04–1.06

0.000

Gender (female)

79.4

64.0

0.42

0.33–0.54

0.000

Hypertension

28.7

62.9

2.97

2.31–3.83

0.000

Hyperlipidemia

11.3

34.0

3.19

2.47–4.13

0.000

Diabetes

6.9

15.8

2.09

1.50–2.92

0.000

Smoking ever

42.6

51.2

1.60

1.25–2.04

0.000

Smoking now

18.3

11.8

0.80

0.55–1.18

0.260

Obesity

17.5

18.3

1.34

0.96–1.86

0.082

Physical inactivity

71.9

73.5

1.00

0.75–1.33

0.993


aIncludes nodules, pulmonal fibrosis, pericarditis, vasculitis, Felty syndrome, and scleritis. CI, confidence interval; QUEST-RA, Questionnaires in Standard Monitoring of Patients with Rheumatoid Arthritis.

Naranjo et al. Arthritis Research & Therapy 2008 10:R30   doi:10.1186/ar2383

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