|
Univariate analyses for cardiovascular morbidity in patients with rheumatoid arthritis in the QUEST-RA study |
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| Cardiovascular morbidity (percentage of patients) |
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|
|
|||||
| No |
Yes |
Hazard ratio |
95% CI |
P value |
|
|
|
|||||
| Rheumatoid variables |
|||||
| Rheumatoid factor |
71.7 |
77.0 |
1.02 |
0.76–1.37 |
0.881 |
| Extra-articular diseasea |
23.0 |
43.3 |
1.52 |
1.19–1.95 |
0.001 |
| Traditional risk factors |
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| Age in years (mean) |
55.8 |
66.4 |
1.05 |
1.04–1.06 |
0.000 |
| Gender (female) |
79.4 |
64.0 |
0.42 |
0.33–0.54 |
0.000 |
| Hypertension |
28.7 |
62.9 |
2.97 |
2.31–3.83 |
0.000 |
| Hyperlipidemia |
11.3 |
34.0 |
3.19 |
2.47–4.13 |
0.000 |
| Diabetes |
6.9 |
15.8 |
2.09 |
1.50–2.92 |
0.000 |
| Smoking ever |
42.6 |
51.2 |
1.60 |
1.25–2.04 |
0.000 |
| Smoking now |
18.3 |
11.8 |
0.80 |
0.55–1.18 |
0.260 |
| Obesity |
17.5 |
18.3 |
1.34 |
0.96–1.86 |
0.082 |
| Physical inactivity |
71.9 |
73.5 |
1.00 |
0.75–1.33 |
0.993 |
|
aIncludes nodules, pulmonal fibrosis, pericarditis, vasculitis, Felty syndrome, and scleritis. CI, confidence interval; QUEST-RA, Questionnaires in Standard Monitoring of Patients with Rheumatoid Arthritis. | |||||
Naranjo et al. Arthritis Research & Therapy 2008 10:R30 doi:10.1186/ar2383 |
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