Table 2

Weighted mean daily faecal blood loss by therapy

Treatment/drug

Studies or study arms (n)

Participants (n)

Weighted mean faecal blood loss (ml/day)

Initial blood loss at start of trial

38

950

0.46

Placebo arm of treatment

14

172

0.76

Aspirin (>1,800 mg/day)

29

361

5.01

Aspirin (325 mg/day)

4

64

1.61

Ibuprofen

4

66

2.03

Fenoprofen

4

62

1.86

Piroxicam

6

60

1.89

Naproxen

4

59

1.98

Indomethacin

6

58

1.39

Etodolac

4

39

0.55

Rofecoxib

1

37

0.80

Diflusinal

4

33

1.68

Ketoprofen

3

28

1.42

Meloxicam

1

26

0.85

Etoricoxib

1

21

0.90

Diclofenac

1

21

0.50

Azapropazone

2

20

1.00

Suoprofen

1

20

1.80

Nefopam

1

19

0.60

Tiaprofen

2

17

0.51

Zomepirac

2

16

6.40

Oxindanac

1

16

1.30

Sulindac

2

15

0.75

Lornoxicam

1

15

0.80

Bromfenac

1

12

2.10

Fluproquazone

1

12

2.80

Nabumetone

1

10

1.60

Oxaprozin

1

10

2.30

Isoxicam

1

8

1.00

Ticlotil

1

8

2.10

Tenoxicam

1

6

1.20

Flurbiprofen

1

6

1.30

Note that all low dose aspirin was 325 mg/day.

Moore et al. Arthritis Research & Therapy 2008 10:R7   doi:10.1186/ar2355