Table 3

Effect of PPAR-γ agonists on incidence of adjuvant arthritis

Group

Experiment


1

2

3


AIA

5/5

6/6

7/7

AIA + ROSI 3

5/6

-

-

AIA + ROSI 10

5/5

7/7

8/8

AIA + PIO 3

6/6

-

-

AIA + PIO 10

6/6

-

-

AIA + PIO 30

6/6

6/7

8/8


PPAR, peroxisome proliferator-activated receptor; AIA, adjuvant-induced arthritis; ROSI, rosiglitazone 3 or 10 mg/kg/day; PIO, pioglitazone 3 or 10 or 30 mg/kg/day. Results are disease incidences at day 21.

Koufany et al. Arthritis Research & Therapy 2008 10:R6   doi:10.1186/ar2354

Open Data