Table 1

Structural parameters of trabecular bone, static indices of bone turnover and biochemical bone turnover measures

Parameter

Men

Women


BV/TV (%)

10.7 ± 4.0

9.8 ± 3.8

BS/BV (mm2/mm3)

22.1 ± 6.5

24.9 ± 8.5

Tb.N (number/mm)

1.1 ± 0.3

1.1 ± 0.3

Tb.Sp (μm)

900 ± 300

900 ± 300

Tb.Th (μm)

100 ± 30

100 ± 30

OS/BS (%)

5.6 ± 7.2

8.2 ± 10.5

ES/BS (%)

2.3 ± 1.9

2.0 ± 1.2

Serum total RANKL (pmol/l)

1,091 ± 781

1,688 ± 2471

Serum OPG (pmol/l)

7.4 ± 2.0

7.4 ± 2.8

Serum ALP (U/l)

92.9 ± 32.7

90.9 ± 19.7

Serum OCN (μg/l)

6.0 ± 3.7

5.8 ± 2.9

Urinary DPD (nmol/mmol creatinine)

18.3 ± 7.4

28.9 ± 7.5

Urinary PYR (nmol/mmol creatinine)

73.7 ± 27.7

102.7 ± 33.7


Results are expressed as mean ± standard deviation. ALP, alkaline phosphatase; BS/BV, specific surface of bone relative to bone tissue volume; BV/TV, bone volume fraction relative to bone tissue volume; DPD, deoxypyridinoline; ES/BS, eroded surface; OCN, osteocalcin; OPG, osteoprotegerin; OS/BS, osteoid surface; PYR, pyridinoline; RANKL, receptor activator of nuclear factor-κB ligand; Tb.N, trabecular number; Tb.Sp, trabecular separation; Tb.Th, trabecular thickness.

Findlay et al. Arthritis Research & Therapy 2008 10:R2   doi:10.1186/ar2348

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