Arthritis Research & Therapy

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Oxaliplatin retains HMGB1 intranuclearly and ameliorates collagen type II-induced arthritis

Therese Östberg*, Heidi Wähämaa, Karin Palmblad, Norimasa Ito, Pernilla Stridh, Maria Shoshan, Michael T Lotze, Helena E Harris and Ulf Andersson

Arthritis Research & Therapy 2008, 10:R1 doi:10.1186/ar2347

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High-mobility group box protein 1 (HMGB1): an alarmin mediating the pathogenesis of rheumatic disease

David S Pisetsky, Helena Erlandsson-Harris, Ulf Andersson Arthritis Research & Therapy 2008, 10:209 (30 June 2008)

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Systemic TNF blockade does not modulate synovial expression of the pro-inflammatory mediator HMGB1 in rheumatoid arthritis patients – a prospective clinical study

Erik Sundberg, Cecilia Grundtman, Erik af Klint, Johan Lindberg, Sofia Ernestam, Ann-Kristin Ulfgren, Helena Harris, Ulf Andersson Arthritis Research & Therapy 2008, 10:R33 (17 March 2008)

Expression of the pro-inflammatory high mobility group box chromosomal protein 1 did not change in any consistent manner over 9 weeks of anti-TNF therapy in nine rheumatoid arthritis patients.