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Abatacept versus other biologics in methotrexate inadequate responders with rheumatoid arthritis: you like tomato and I like tomahto... let's call the whole thing off
Yusuf Yazici Arthritis Research & Therapy 2012, 14:104 (21 February 2012)
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Regulation of inflammatory arthritis by the upstream kinase mitogen activated protein kinase kinase 7 in the c-Jun N-Terminal kinase pathway
Sang-il Lee, David L Boyle, Andres Berdeja, Gary S Firestein Arthritis Research & Therapy 2012, 14:R38 (21 February 2012)
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Endothelial progenitor cells: a new player in lupus?
Sahena Haque, M Yvonne Alexander, Ian N Bruce Arthritis Research & Therapy 2012, 14:203 (20 February 2012)
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Autonomic dysfunction in women with fibromyalgia
J Derek Kingsley Arthritis Research & Therapy 2012, 14:103 (20 February 2012)
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Contributions of mass spectrometry-based proteomics to defining cellular mechanisms and diagnostic markers for systemic lupus erythematosus
Erik A Korte, Patrick M Gaffney, David W Powell Arthritis Research & Therapy 2012, 14:204 (20 February 2012)
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Erectile dysfunction is frequent in systemic sclerosis and associated with severe disease. A study of the EULAR Scleroderma Trial and Research (EUSTAR) group
Chingching Foocharoen, Alan Tyndall, Eric Hachulla, Edoardo Rosato, Yannick Allanore, Dominique Farge-Bancel, Paola Caramaschi, Paolo Airo, Starovojtova M Nikolaevna, Jose Antonio Pereira da Silva, Bojana Stamenkovic, Gabriela Riemekasten, Simona Rednic, Jean Sibilia, Piotr Wiland, Ingo Tarner, Vanessa Smith, Anna T Onken, Walid AHMED ABDEL ATTY Mohamed, Oliver Distler, Jadranka Morovic-Vergles, Andrea Himsel, Paloma Garcia de la Pena Lefebvre, Thomas Hugle, Ulrich A Walker Arthritis Research & Therapy 2012, 14:R37 (20 February 2012)
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Editor’s summary
Severe erectile dysfunction is common amongst men with systemic sclerosis, appearing relatively early after disease diagnosis and associated with age; low treatment coverage suggests increased physician awareness is required.
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Renal expression and serum levels of high mobility group box 1 protein in lupus nephritis
Agneta Zickert, Karin Palmblad, Birgitta Sundelin, Sangeeta Chavan, Kevin J Tracey, Annette Bruchfeld, Iva Gunnarsson Arthritis Research & Therapy 2012, 14:R36 (20 February 2012)
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Editor’s summary
Serum levels of high mobility group box 1 protein (HMGB1) are significantly increased in patients with lupus nephritis and remain raised after the initiation of immunosuppressive therapy, possibly indicating persistent inflammatory activity.
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Anti-citrullinated fibronectin antibodies in rheumatoid arthritis are associated with HLA-DRB1 shared epitope alleles.
Joyce JBC van Beers, Annemiek Willemze, Judith Stammen-Vogelzangs, Jan W Drijfhout, Rene EM Toes, Ger JM Pruijn Arthritis Research & Therapy 2012, 14:R35 (17 February 2012)
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Serum levels of CXCL13 are associated with ultrasonographic synovitis and predict power Doppler persistence in early rheumatoid arthritis treated with non-biological disease-modifying anti-rheumatic drugs
Serena Bugatti, Antonio Manzo, Francesca Benaglio, Catherine Klersy, Barbara Vitolo, Monica Todoerti, Garifallia Sakellariou, Carlomaurizio Montecucco, Roberto Caporali Arthritis Research & Therapy 2012, 14:R34 (15 February 2012)
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Atacicept in combination with MMF and corticosteroids in lupus nephritis: results of a prematurely terminated trial
Ellen M Ginzler, Stephen Wax, Anand Rajeswaran, Samuel Copt, Jan Hillson, Eleanor Ramos, Nora G Singer Arthritis Research & Therapy 2012, 14:R33 (10 February 2012)
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Interleukin-10 produced by B cells is crucial for the suppression of Th17/Th1 responses, induction of T regulatory type 1 cells and reduction of collagen-induced arthritis
Natalie A Carter, Elizabeth C Rosser, Claudia Mauri Arthritis Research & Therapy 2012, 14:R32 (8 February 2012)
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Direct transplantation of mesenchymal stem cells into the knee joints of Hartley Strain guinea pig with spontaneous osteoarthritis
Mitsuhiko Sato, Kenzo Uchida, Hideaki Nakajima, Tsuyoshi Miyazaki, Alexander Rodriguez Guerrero, Shuji Watanabe, Sally Roberts, Hisatoshi Baba Arthritis Research & Therapy 2012, 14:R31 (7 February 2012)
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Baseline serum MMP-3 levels in patients with Rheumatoid Arthritis are still independently predictive of radiographic progression in a longitudinal observational cohort at 8 years follow up
Mark Houseman, Catherine Potter, Nicola Marshall, Rachel Lakey, Tim Cawston, Ian Griffiths, Steven Young-Min, John D Isaacs Arthritis Research & Therapy 2012, 14:R30 (7 February 2012)
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The neuropeptide neuromedin U promotes autoantibody-mediated arthritis
Sindhuja M Rao, Jennifer L Auger, Philippe Gaillard, Ralph Weissleder, Etsuko Wada, Richard Torres, Masayasu Kojima, Christophe Benoist, Diane Mathis, Bryce A Binstadt Arthritis Research & Therapy 2012, 14:R29 (7 February 2012)
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Editor’s summary
Neuromedin U (NMU), a neuropeptide produced by bone-marrow-derived cells, promotes autoantibody-mediated arthritis in mice, suggesting NMU may be a potential therapeutic target in inflammatory arthritis.
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Low copy number of the FCGR3B gene and rheumatoid arthritis: a case control study and meta-analysis
Scott W Graf, Sue Lester, Hans Nossent, Catherine L Hill, Susanna Proudman, Anita Lee, Maureen Rischmueller Arthritis Research & Therapy 2012, 14:R28 (7 February 2012)
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Pre-disease pregnancy complications and systemic sclerosis: pathogenic or pre-clinical?
Eliza Chakravarty Arthritis Research & Therapy 2012, 14:102 (6 February 2012)
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Takayasu's arteritis is associated with HLA-B*52, but not with B*51, in Turkey
Ziver Sahin, Muge Bicakcigil, Kenan Aksu, Sevil Kamali, Servet Akar, Fatos Onen, Omer Karadag, Zeynep Ozbalkan, Askin Ates, Huseyin T E Ozer, Vuslat Yilmaz, Emire Seyahi, Mehmet A Ozturk, Ayse Cefle, Veli Cobankara, Ahmet M Onat, Ercan Tunc, Nursen Duzgun, Sibel Z Aydin, Neslihan Yilmaz, Izzet Fresko, Yasar Karaaslan, Sedat Kiraz, Nurullah Akkoc, Murat Inanc, Gokhan Keser, Fatma A Uyar, Haner Direskeneli, Guher S Direskeneli Arthritis Research & Therapy 2012, 14:R27 (6 February 2012)
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An in vivo investigation of the initiation and progression of subchondral cysts in a rodent model of secondary osteoarthritis
David D McErlain, Veronica Ulici, Mark R Darling, Joe S Gati, Vasek Pitelka, Frank Beier, David W Holdsworth Arthritis Research & Therapy 2012, 14:R26 (3 February 2012)
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Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies
Chih Liu, Stephanie Tangsombatvisit, Jacob M Rosenberg, Gil Mandelbaum, Emily C Gillespie, Or P Gozani, Ash A Alizadeh, Paul J Utz Arthritis Research & Therapy 2012, 14:R25 (2 February 2012)
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Therapy of lupus nephritis: lessons learned from clinical research and daily care of patients
Frédéric A Houssiau Arthritis Research & Therapy 2012, 14:202 (31 January 2012)
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A profile of immune response to herpesvirus is associated with radiographic joint damage in rheumatoid arthritis
John M Davis, Keith L Knutson, John A Skinner, Michael A Strausbauch, Cynthia S Crowson, Terry M Therneau, Peter J Wettstein, Eric L Matteson, Sherine E Gabriel Arthritis Research & Therapy 2012, 14:R24 (31 January 2012)
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Is there any scientific evidence for the use of glucosamine in the management of human osteoarthritis?
Yves Henrotin, Ali Mobasheri, Marc Marty Arthritis Research & Therapy 2012, 14:201 (30 January 2012)
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Extracellular nicotinamide phosphoribosyltransferase (NAMPT/visfatin) inhibits insulin-like growth factor-1 signaling and proteoglycan synthesis in human articular chondrocytes
Raghunatha R Yammani, Richard F Loeser Arthritis Research & Therapy 2012, 14:R23 (30 January 2012)
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Predictors of survival in a cohort of patients with polymyositis and dermatomyositis: effect of corticosteroids, methotrexate, and azathioprine
Elena Schiopu, Kristine Phillips, Paul M MacDonald, Leslie J Crofford, Emily C Somers Arthritis Research & Therapy 2012, 14:R22 (27 January 2012)
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A randomised controlled trial of a self-management education program for osteoarthritis of the knee delivered by health care professionals
Sophie Coleman, N Kathryn Briffa, Graeme Carroll, Charles Inderjeeth, Nicola Cook, Jean McQuade Arthritis Research & Therapy 2012, 14:R21 (27 January 2012)
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