Arthritis Research & Therapy | Research articles

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Research articles

All research articles published in Arthritis Research & Therapy are open access which means they are freely and universally available online.

Research article

Apoptotic cell-mediated suppression of streptococcal cell wall-induced arthritis is associated with alteration of macrophage function and local regulatory T cell increase: a potential cell-based therapy?
Sylvain Perruche, Philippe Saas, Wan Jun Chen
Arthritis Research & Therapy 2009, 11:R104 (1 July 2009)
[Abstract] [Provisional PDF]

Research article

Antibodies to cyclic citrullinated protein and erythrocyte sedimentation rate predict hand bone loss in patients with rheumatoid arthritis of short duration: a longitudinal study
Pernille Boyesen, Mari Hoff, Sigrid Odegard, Glenn Haugeberg, Silje W Syversen, Per I Gaarder, Cecilie Okkenhaug, Tore K Kvien
Arthritis Research & Therapy 2009, 11:R103 (1 July 2009)
[Abstract] [Provisional PDF]

Research article

Broad-range PCR, cloning and sequencing of the full 16S rRNA gene for detection of bacterial DNA in synovial fluid samples of Tunisian patients with reactive and undifferentiated arthritis
Mariam Siala, Radhouane Gdoura, Hela Fourati, Markus Rihl, Benoit Jaulhac, Mohamed Younes, Jean Sibilia, Sofien Baklouti, Naceur Bargaoui, Slaheddine Sellami, Abdelghani Sghir, Adnane Hammami
Arthritis Research & Therapy 2009, 11:R102 (1 July 2009)
[Abstract] [Provisional PDF]

Research article

Increased production of soluble CTLA-4 in patients with spondylarthropathies correlates with disease activity
Eric Toussirot, Philippe Saas, Marina Deschamps, Fabienne Pouthier, Lucille Perrot, Sylvain Perruche, Jacqueline Chabod, Pierre Tiberghien, Daniel Wendling
Arthritis Research & Therapy 2009, 11:R101 (1 July 2009)
[Abstract] [Provisional PDF]

Research article

Myeloid dendritic cells correlate with clinical response whereas plasmacytoid dendritic cells impact autoantibody development in rheumatoid arthritis patients treated with infliximab
Christophe Richez, Thierry Schaeverbeke, Chantal Dumoulin, Joel Dehais, Jean-Francois Moreau, Patrick Blanco
Arthritis Research & Therapy 2009, 11:R100 (29 June 2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article

Early and long-standing rheumatoid arthritis: distinct molecular signatures identified by gene-expression profiling in synovia
Thierry Lequerre, Carine Bansard, Olivier Vittecoq, Celine Derambure, Martine Hiron, Maryvonne Daveau, Francois Tron, Xavier Ayral, Norman Biga, Isabelle Auquit-Auckbur, Gilles Chiocchia, Xavier Le Loet, Jean-Philippe Salier
Arthritis Research & Therapy 2009, 11:R99 (29 June 2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article

Exercise therapy for the management of osteoarthritis of the hip joint: a systematic review
Peter J McNair, Marian A Simmonds, Mark G Boocock, Peter J Larmer
Arthritis Research & Therapy 2009, 11:R98 (25 June 2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article

A prospective study of androgen levels, hormone related genes and risk of rheumatoid arthritis
Elizabeth W Karlson, Lori B Chibnik, Monica McGrath, Shun-Chiao Chang, Brendan T Keenan, Karen H Costenbader, Patricia A Fraser, Shelley Tworoger, Susan E Hankinson, I-Min Lee, Julie Buring, Immaculata De Vivo
Arthritis Research & Therapy 2009, 11:R97 (25 June 2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article

Degradome expression profiling in human articular cartilage
Tracey E Swingler, Jasmine G Waters, Rosemary K Davidson, Caroline J Pennington, Xose S Puente, Clare Darrah, Adele Cooper, Simon T Donell, Geoffrey R Guile, Wenjia Wang, Ian M Clark
Arthritis Research & Therapy 2009, 11:R96 (23 June 2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article

Masitinib in the treatment of active rheumatoid arthritis: results of a multicentre, open-label, dose-ranging, phase 2a study
Jacques Tebib, Xavier Mariette, Pierre Bourgeois, René-Marc Flipo, Philippe Gaudin, Xavier Le Loët, Paul Gineste, Laurent Guy, Colin D Mansfield, Alain Moussy, Patrice Dubreuil, Olivier Hermine, Jean Sibilia
Arthritis Research & Therapy 2009, 11:R95 (23 June 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article

The utility of MRI in predicting radiographic erosions in the metatarsophalangeal joints of the rheumatoid foot: a prospective longitudinal cohort study
Matthew L Mundwiler, Paul Maranian, Douglas H Brown, Jeffrey M Silverman, Daniel Wallace, Dinesh Khanna, James Louie, Daniel E Furst, Michael H Weisman
Arthritis Research & Therapy 2009, 11:R94 (22 June 2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article

Antiphospholipid antibody profiles in lupus nephritis with glomerular microthrombosis: a prospective study of 124 cases
Hui Zheng, Yi Chen, Wen Ao, Yan Shen, Xiao-wei Chen, Min Dai, Xiao-dong Wang, Yu-cheng Yan, Cheng-de Yang
Arthritis Research & Therapy 2009, 11:R93 (22 June 2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article

Synovial fluid level of aggrecan ARGS fragments is a more sensitive marker of joint disease than glycosaminoglycan or aggrecan levels: a cross-sectional study
Staffan Larsson, L Stefan Lohmander, Andre Struglics
Arthritis Research & Therapy 2009, 11:R92 (22 June 2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article

Negative association of the chemokine receptor CCR5 d32 polymorphism with systemic inflammatory response, extra-articular symptoms and joint erosion in rheumatoid arthritis
Manuela Rossol, Matthias Pierer, Sybille Arnold, Gernot KeySZer, Harald Burkhardt, Christoph Baerwald, Ulf Wagner
Arthritis Research & Therapy 2009, 11:R91 (18 June 2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article

Relationship of compartment-specific structural knee status at baseline with change in cartilage morphology: a prospective observational study using data from the osteoarthritis initiative
Felix Eckstein, Wolfgang Wirth, Martin I Hudelmaier, Susanne Maschek, Wolfgang Hitzl, Bradley T Wyman, Michael Nevitt, Marie-Pierre Hellio Le Graverand, David Hunter, the OA Initiative Investigator Group
Arthritis Research & Therapy 2009, 11:R90 (17 June 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article

Can health care databases be used to identify incident cases of osteonecrosis?
Steven C Vlad, David T Felson, Donald R Miller
Arthritis Research & Therapy 2009, 11:R89 (17 June 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article

Smoking and nicotine exposure delay development of collagen-induced arthritis in mice
Sofia S Lindblad, Piotr Mydel, Ing-Marie Jonsson, Robert M Senior, Andrej Tarkowski, Maria Bokarewa
Arthritis Research & Therapy 2009, 11:R88 (11 June 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article

Anti-C1q antibodies antedate patent active glomerulonephritis in patients with systemic lupus erythematosus
Olivier C Meyer, Pascale Nicaise-Roland, Nolwenn Cadoudal, Sabine Grootenboer-Mignot, Elisabeth Palazzo, Gilles Hayem, Philippe Dieudé, Sylvie Chollet-Martin
Arthritis Research & Therapy 2009, 11:R87 (10 June 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article