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 Welcome to Arthritis Research & Therapy
  Translating research into clinical practice
  Editors-in-Chief: Peter E Lipsky, Bethesda, USA and Ravinder N Maini, London, UK

 
 
 
 
Research highlight: Glucocorticoid sensitivity influences arthritis development    Open Access
Glucocorticoid receptor gene polymorphisms ER22/23EK and 9beta are associated with an enhanced predisposition to develop rheumatoid arthritis and suggest a role for constitutionally determined glucocorticoid sensitivity in auto-immunity development.
Arthritis Research & Therapy 2010, 12:R159

Latest articles

Research article    
Predictors of interstitial lung disease in early systemic sclerosis: a prospective longitudinal study of the GENISOS cohort
Shervin Assassi, Roozbeh Sharif, Robert E Lasky, Terry A McNearney, Rosa M Estrada-Y-Martin, Hilda T Draeger, Deepthi K Nair, Marvin J Fritzler, John D Reveille, Frank C Arnett, Maureen D Mayes, The GENISOS Study
Arthritis Research & Therapy 2010, 12:R166 (2 September 2010)
[Abstract] [Provisional PDF]




Review   
New developments in osteoarthritis. Prevention of injury-related knee osteoarthritis: opportunities for the primary and secondary prevention of knee osteoarthritis
Charles R Ratzlaff, Matthew H Liang
Arthritis Research & Therapy 2010, 12:215 (31 August 2010)
[PDF]




Research article    
High mobility group box 1 potentiates the pro-inflammatory effects of interleukin-1beta in osteoarthritic synoviocytes
Isabel Garcia-Arnandis, Maria Isabel Guillen, Francisco Gomar, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Maria Jose Alcaraz
Arthritis Research & Therapy 2010, 12:R165 (27 August 2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles]




Research article    
Circulating mediators of bone remodeling in psoriatic arthritis: implications for disordered osteoclastogenesis and bone erosion
Nicola Dalbeth, Bregina Pool, Timothy Smith, Karen E Callon, Maria Lobo, William J Taylor, Peter B Jones, Jillian Cornish, Fiona M McQueen
Arthritis Research & Therapy 2010, 12:R164 (26 August 2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles]




Editorial    
A new tool for detection of type I interferon activation in systemic lupus erythematosus
Kyriakos A Kirou, George D Kalliolias
Arthritis Research & Therapy 2010, 12:138 (26 August 2010)
[PDF]




Research article    
The effect of risedronate on osteogenic lineage is mediated by cyclooxygenase-2 gene upregulation
Maria Teresa Valenti, Sandro Giannini, Luca Donatelli, Mirko Zanatta, Francesco Bertoldo, Stefania Sella, Maria Teresa Vilei, Elena Ossi, Giuseppe Realdi, Vincenzo Lo Cascio, Luca Dalle Carbonare
Arthritis Research & Therapy 2010, 12:R163 (25 August 2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles]




The Scientific Basis of Rheumatology: A Decade of Progress

To mark its 10th anniversary, Arthritis Research & Therapy is publishing a freely available, four-part collection of new review articles.
This special issue provides an in depth overview of the current status of basic and clinical research in rheumatology.

Complete collection free online





All articles published in supplements are fully peer reviewed.

Latest free review article   

The following article has recently become free to access:

Review 
A role for age-related changes in TGFβ signaling in aberrant chondrocyte differentiation and osteoarthritis
Peter M van der Kraan, Esmeralda N Blaney Davidson, Wim B van den Berg
Arthritis Research & Therapy 2010, 12:201 (29 January 2010)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

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